Evidence map›Paper›PMID 35465423›Full record

ArticleFrontiers in surgery2022

Which Role for Hyperbaric Oxygen Therapy in the Treatment of Fournier's Gangrene? A Retrospective Study.

Roberta Tutino, Francesco Colli, Giovanna Rizzo, Sebastiano Bonventre, Gregorio Scerrino, Giuseppe Salamone, Giuseppina Melfa, Giuseppina Orlando, Gaetano Gallo, Mauro Santarelli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Roberta TutinoChirurgia 3, Dipartimento di Chirurgia Generale e Specialistica, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
Francesco ColliDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Giovanna RizzoDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Sebastiano BonventreDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Gregorio ScerrinoDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Giuseppe SalamoneDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Giuseppina MelfaDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Giuseppina OrlandoDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
Gaetano GalloDepartment of General Surgery, University of Catanzaro, Catanzaro, Italy.
Mauro SantarelliChirurgia 3, Dipartimento di Chirurgia Generale e Specialistica, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
Marco MassaniChirurgia 1, Ospedale Regionale di Treviso, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy.
Gianfranco CocorulloDepartment of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.
University of Palermo · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda ULSS 9 TREVISO · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In Fournier's gangrene, surgical debridement plus antimicrobial therapy is the mainstay of treatment but can cause a great loss of tissue. The disease needs long hospital stays and, despite all, has a high mortality rate. The aim of our study is to investigate if factors, such as hyperbaric therapy, can offer an improvement in prognosis. Methods: We retrospectively evaluated data on 23 consecutive patients admitted for Fournier's gangrene at the University Hospital "P. Giaccone" of Palermo from 2011 to 2018. Factors related to length of hospital stay and mortality were examined. Results: Mortality occurred in three patients (13.1%) and was correlated with the delay between admission and surgical operation [1.7 days (C.I. 0.9-3.5) in patients who survived vs. 6.8 days (C.I. 3.5-13.4) in patients who died ( Conclusion: Our study proves that a delay in the treatment of patients with Fournier's gangrene has a correlation with the mortality rate, while the use of hyperbaric oxygen therapy seems to not improve the survival rate, increasing the hospital stay instead.

Indexed as

fasciitisFournier's gangrenehyperbaric therapynecrosisperineum

Identifiers

PMID35465423
PMCPMC9018989
OpenAlexW4226158027

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.