Evidence map›Paper›PMID 35465281›Full record

ReviewTzu chi medical journal

Hepatitis C virus core protein: Not just a nucleocapsid building block, but an immunity and inflammation modulator.

Hemalatha Mani, Jui-Hung Yen, Hao-Jen Hsu, Chun-Chun Chang, Je-Wen Liou

Open access · diamondAbstract readReview
In one paragraph

Review in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hemalatha ManiInstitute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Jui-Hung YenDepartment of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan.
Hao-Jen HsuDepartment of Life Sciences, Tzu Chi University, Hualien, Taiwan.
Chun-Chun ChangDepartment of Laboratory Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Je-Wen LiouInstitute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Tzu Chi University · TWTzu Chi Foundation · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coevolution occurs between viruses and their hosts. The hosts need to evolve means to eliminate pathogenic virus infections, and the viruses, for their own survival and multiplication, have to develop mechanisms to escape clearance by hosts. Hepatitis C virus (HCV) of

Indexed as

Hepatitis C virus core proteinHost immunityInflammation modulationVirus persistent infection

Identifiers

PMID35465281
PMCPMC9020238
OpenAlexW3203922752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.