ArticlePhysiology and molecular biology of plants : an international journal of functional plant biology2022
Meta-QTLs, ortho-MetaQTLs and candidate genes for grain Fe and Zn contents in wheat (
Article in Physiology and molecular biology of plants : an international journal of functional plant biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Meta-QTL s and haplotypes for efficient zinc biofortification of rice.The plant genome · 2023Pooled it
- Deciphering key genomic regions controlling flag leaf size in wheat via integration of meta-QTL and in silico transcriptome assessment.BMC genomics · 2023Pooled it
- Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century.Journal of integrative plant biology · 2026Review
- Quantitative trait loci associated with drought stress tolerance in wheat primed with zinc oxide nanoparticles at seed germination and seedling stages.Scientific reports · 2026Article
- Further studies on pyramiding of alien genes for high grain Fe and Zn in bread wheat.Molecular breeding : new strategies in plant improvement · 2025Article
- Integrated meta-QTL and in silico transcriptome assessment pinpoint major genomic regions responsible for spike length in wheat (Triticum aestivum L.).The plant genome · 2024Article
- Biofortification of Triticum species: a stepping stone to combat malnutrition.BMC plant biology · 2024Review
- Molecular characterization of QTL for grain zinc and iron concentrations in wheat landrace Chinese Spring.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Meta-QTL analysis and candidate genes for quality traits, mineral content, and abiotic-related traits in wild emmer.Frontiers in plant science · 2024Article
- Meta-QTL analysis in wheat: progress, challenges and opportunities.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
- Genetic analysis of iron, zinc and grain yield in wheat-Aegilops derivatives using multi-locus GWAS.Molecular biology reports · 2023Article
- Meta-QTLs, ortho-meta QTLs and related candidate genes for yield and its component traits under water stress in wheat (Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Discovering Loci for Breeding Prospective and Phenology in Wheat Mediterranean Landraces by Environmental and eigenGWAS.International journal of molecular sciences · 2023Article
- Consensus genomic regions associated with grain protein content in hexaploid and tetraploid wheat.Frontiers in genetics · 2022Article
- A consensus map for quality traits in durum wheat based on genome-wide association studies and detection of ortho-meta QTL across cereal species.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Majority of cereals are deficient in essential micronutrients including grain iron (GFe) and grain zinc (GZn), which are therefore the subject of research involving biofortification. In the present study, 11 meta-QTLs (MQTLs) including nine novel MQTLs for GFe and GZn contents were identified in wheat. Eight of these 11 MQTLs controlled both GFe and GZn. The confidence intervals of the MQTLs were narrower (0.51-15.75 cM) relative to those of the corresponding QTLs (0.6 to 55.1 cM). Two ortho-MQTLs involving three cereals (wheat, rice and maize) were also identified. Results of MQTLs were also compared with the results of earlier genome wide association studies (GWAS). As many as 101 candidate genes (CGs) underlying MQTLs were also identified. Twelve of these CGs were prioritized; these CGs encoded proteins with important domains (zinc finger, RING/FYVE/PHD type, flavin adenine dinucleotide linked oxidase, etc.) that are involved in metal ion binding, heme binding, iron binding, etc. qRT-PCR analysis was conducted for four of these 12 prioritized CGs using genotypes which have differed for GFe and GZn. Significant differential expression in these genotypes was observed at 14 and 28 days after anthesis. The MQTLs/CGs identified in the present study may be utilized in marker-assisted selection (MAS) for improvement of GFe/GZn contents and also for understanding the molecular basis of GFe/GZn homeostasis in wheat. Supplementary Information: The online version contains supplementary material available at 10.1007/s12298-022-01149-9.
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