Evidence map›Paper›PMID 35465189›Full record

ArticleCardiology and cardiovascular medicine2022

Perioperative Outcomes of Acute Type-A Aortic Dissection Repair was Unaffected by COVID-19 Testing Delay.

Felix Orelaru, Elizabeth L Norton, Rana-Armaghan Ahmad, Aroma Naeem, Karen M Kim, Shinichi Fukuhara, Himanshu J Patel, G Michael Deeb, Bo Yang

Abstract read
In one paragraph

Article in Cardiology and cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Felix OrelaruDepartment of General Surgery, St. Joseph Mercy, Ann Arbor, Michigan, USA.
Elizabeth L NortonDivision of Cardiothoracic Surgery, Department of Surgery, Emory University, Atlanta, Georgia.
Rana-Armaghan AhmadDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
Aroma NaeemDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
Karen M KimDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
Shinichi FukuharaDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
Himanshu J PatelDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
G Michael DeebDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.
Bo YangDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan, USA.

Funding

Therapeutic Insights into Loeys-Dietz Syndrome using Humanized ModelsR01HL151776 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bo Yang · 2020 to 2026
$4.2M
Define the mechanisms of aortopathy in bicuspid aortic valve patientsR01HL141891 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2018 to 2022
$3.5M
Effect of mutations in the TGF-beta pathway genes on smooth muscle cell differentiation using patient derived iPSCs.K08HL130614 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2016 to 2020
$848k
NHLBI NIH HHS K08 HL130614NHLBI NIH HHS R01 HL141891NHLBI NIH HHS R01 HL151776
6 · The paper itself

Abstract

Background: This study assesses impact of COVID-19 testing delay on perioperative outcomes of Acute Type A Aortic Dissection (ATAAD) repair at a single institution. Methods: From January 2010 - May 2021, 539 ATAAD patients underwent open aortic repair at our institution. Sixty-five of these patients had open aortic repair during COVID (March 2020 - May 2021) and 474 patients were pre-COVID (January 2010 - February 2020). Results: Compared to the pre-COVID group, patients During-COVID had a higher proportion of previous myocardial ischemia [9/65 (14%) vs 28/474 (5.9%), p=0.03], chronic obstructive pulmonary disease [14/65 (22%) vs 55/474 (12%), p=0.02], and renal malperfusion syndrome [11/65 (17%) vs 30/474 (6.4%), p=0.01]. There was no significant difference in surgical outcomes between groups, including operative mortality (7.6% vs 9.2%, p=0.64). The median admission-to-Operating Room (OR) time was 107 minutes in the During-COVID group compared to 87 minutes in pre-COVID group, p=0.88. During COVID, the median admission-to-OR time was significantly longer in the Waiting group compared to the No-waiting group (209 min vs 75min, p=0.0009). Only one patient had positive COVID test. There were no aortic ruptures while awaiting COVID testing results. There was a total of 6 reported deaths in the During-COVID group: 1 patient died post-surgery due to ARDS caused by COVID, and others due to ischemic stroke (3 patients) and organ failure (2 patients). Conclusions: Perioperative outcomes of ATAAD patients were similar during-COVID compared to pre-COVID. Waiting for COVID testing results did not significantly affect the perioperative outcomes among ATAAD patients after repair.

Indexed as

Aortic dissectionCOVID-19OutcomesThoracic aortic repair

Identifiers

PMID35465189
PMCPMC9030690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.