Evidence map›Paper›PMID 35465180›Full record

ArticleApplied bionics and biomechanics2022

Benefits of Contrast-Enhanced Ultrasonography to the Differential Diagnosis of TI-RADS 4-5 Thyroid Nodules.

Ping Yu, Sihua Niu, Shuang Gao, Hui Tian, Jiaan Zhu

RetractedAbstract readRetracted Publication
In one paragraph

Article in Applied bionics and biomechanics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ping YuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing 100044, China.
Sihua NiuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing 100044, China.
Shuang GaoDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing 100044, China.
Hui TianDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing 100044, China.
Jiaan ZhuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing 100044, China.ORCID https://orcid.org/0000-0001-8700-639X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The early detection, diagnosis, and treatment of thyroid cancer are of great significance to the prognosis for patients. This study was aimed at exploring the benefits of contrast-enhanced ultrasonography (CEUS) to the differential diagnosis of thyroid nodules classified as TI-RADS class 4 or 5. Method: A total of 46 patients with TI-RADS 4-5 thyroid nodules admitted in Peking University People's Hospital from January 2019 to January 2021 were selected to study. The sensitivity, specificity, accuracy, and positive and negative predictive values of conventional ultrasonography (US) and conventional ultrasonography combined with contrast-enhanced ultrasonography (US + CEUS) in the diagnosis of benign and malignant thyroid nodules were compared by referring to the results of the surgical pathology report, which is seen as the "gold standard" for diagnosis, followed by the construction of receiver operating characteristic curves (ROCs). Result: Among 57 thyroid nodules, there were statistically significant differences between benign and malignant thyroid nodules in terms of echogenicity, margin characteristics, aspect ratio, and calcification ( Conclusion: Using US + CEUS to diagnose thyroid nodules classified as TI-RADS category 4 or 5 can further improve distinguishing between benign and malignant nodules. The CEUS is of important value to clinical applications as it can provide effective supplementary information and quantitative analysis for the differentiation between benign and malignant thyroid nodules.

Identifiers

PMID35465180
PMCPMC9033405

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