ArticleTechnical innovations & patient support in radiation oncology2022
Evaluation of an automated template-based treatment planning system for radiotherapy of anal, rectal and prostate cancer.
Article in Technical innovations & patient support in radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Innovative radiotherapy approaches.ESMO gastrointestinal oncology · 2026Review
- Best Practice: CT-guided Adaptive Radiotherapy Reference Planning on the Ethos Platform.Journal of applied clinical medical physics · 2026Review
- Early Experience Comparing Reduced Planning Target Volume Margins Using Cone Beam Computed Tomography Scan Guided Online Adaptive Radiation Therapy to Nonadaptive, Traditional Margin Plans for Muscle-Invasive Bladder Cancer.Advances in radiation oncology · 2026Article
- Leveraging High-Fidelity Mode for Improved Online Adaptive Stereotactic Accelerated Partial Breast Treatment Efficiency.Advances in radiation oncology · 2025Article
- Strategies to reduce intestinal toxicity in neoadjuvant management of locally advanced rectal cancer.Discover oncology · 2025Review
- AI-driven online adaptive radiotherapy in prostate cancer treatment: considerations on activity time and dosimetric benefits.Radiation oncology (London, England) · 2025Article
- Evaluating CBCT-Guided Adaptive Radiotherapy for Pancreatic Cancer Using Synthetic CBCT Data.Current oncology (Toronto, Ont.) · 2025Article
- Quantitative Evaluation of a Fully Automated Planning Solution for Prostate-Only and Whole-Pelvic Radiotherapy.Cancers · 2024Article
- Optimizing volumetric modulated arc therapy prostate planning using an automated Fine-Tuning process through dynamic adjustment of optimization parameters.Physics and imaging in radiation oncology · 2024Article
- Feasibility of Ethos adaptive treatments of lung tumors and associated quality assurance.Journal of applied clinical medical physics · 2024Article
- A retrospective study on the investigation of potential dosimetric benefits of online adaptive proton therapy for head and neck cancer.Journal of applied clinical medical physics · 2024Article
- ROAR-A: re-optimization based Online Adaptive Radiotherapy of anal cancer, a prospective phase II trial protocol.BMC cancer · 2024Article
- Evaluation of Ethos intelligent optimization engine for left locally advanced breast cancer.Frontiers in oncology · 2024Article
- A head and neck treatment planning strategy for a CBCT-guided ring-gantry online adaptive radiotherapy system.Journal of applied clinical medical physics · 2023Article
- Physicists should perform reference planning for CBCT guided online adaptive radiotherapy.Journal of applied clinical medical physics · 2023Article
- Article
- Review of cone beam computed tomography based online adaptive radiotherapy: current trend and future direction.Radiation oncology (London, England) · 2023Review
- Dosimetric comparison between intensity-modulated radiation therapy and volumetric-modulated arc therapy to enhance bladder and bowel.Journal of medicine and life · 2023Article
- Investigating the feasibility of using Ethos generated treatment plans for head and neck cancer patients.Technical innovations & patient support in radiation oncology · 2023Article
- A roadmap for implementation of kV-CBCT online adaptive radiation therapy and initial first year experiences.Journal of applied clinical medical physics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and purpose: The Ethos system has enabled online adaptive radiotherapy (oART) by implementing an automated treatment planning system (aTPS) for both intensity-modulated radiotherapy (IMRT) and volumetric modulated arc radiotherapy (VMAT) plan creation. The purpose of this study is to evaluate the quality of aTPS plans in the pelvic region. Material and Methods: Sixty patients with anal (n = 20), rectal (n = 20) or prostate (n = 20) cancer were retrospectively re-planned with the aTPS. Three IMRT (7-, 9- and 12-field) and two VMAT (2 and 3 arc) automatically generated plans (APs) were created per patient. The duration of the automated plan generation was registered. The best IMRT-AP and VMAT-AP for each patient were selected based on target coverage and dose to organs at risk (OARs). The AP quality was analyzed and compared to corresponding clinically accepted and manually generated VMAT plans (MPs) using several clinically relevant dose metrics. Calculation-based pre-treatment plan quality assurance (QA) was performed for all plans. Results: The median total duration to generate the five APs with the aTPS was 55 min, 39 min and 35 min for anal, prostate and rectal plans, respectively. The target coverage and the OAR sparing were equivalent for IMRT-APs and VMAT-MPs, while VMAT-Aps.demonstrated lower target dose homogeneity and higher dose to some OARs. Both conformity and homogeneity index were equivalent (rectal) or better (anal and prostate) for IMRT-APs compared to VMAT-MPs. All plans passed the patient-specific QA tolerance limit. Conclusions: The aTPS generates plans comparable to MPs within a short time-frame which is highly relevant for oART treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.