ArticleFrontiers in bioengineering and biotechnology2022
The Mismatch Between Bony Endplates and Grafted Bone Increases Screw Loosening Risk for OLIF Patients With ALSR Fixation Biomechanically.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 39 citations in OpenAlex.
- Impact of endplate-graft geometric matching on cage subsidence following stand-alone lateral lumbar interbody fusion: a finite element analysis.BMC musculoskeletal disorders · 2026Article
- Meniscal centralization restores meniscus-cartilage contact mechanics after posterior root repair: a biomechanical in-silico study.Journal of orthopaedic surgery and research · 2026Article
- Disc collapse aggravates vertebral recollapse following percutaneous kyphoplasty: a clinical review and biomechanical study.Quantitative imaging in medicine and surgery · 2026Article
- Changes in PFNA nail position do not influence bone healing and femoral head varus in patients with stable intertrochanteric fractures: a comprehensive clinical and biomechanical study.European journal of medical research · 2026Article
- Degenerative scoliosis may trigger higher incidence of adjacent vertebral fractures following percutaneous vertebroplasty: a clinical evidence-based biomechanical research.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Non-Contiguous OVCF Patients Had a Higher Risk of AVF After PVP Operation Related to Poor Bone Mineral Density Rather Than Aggravated Stress Concentration.Clinical interventions in aging · 2026Article
- Single-Side Iatrogenic Pedicle Injury May Trigger an Increased Risk of Contralateral Screw Loosening: An In Silico Study.JOR spine · 2025Article
- Sagittal-oriented articular processes and intervertebral disc degeneration phenotypes can concurrently lead to an increased presence of annulus tears in the cranial adjacent motion segment : a clinical review and biomechanical simulation.Bone & joint research · 2025Article
- Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients.BMC musculoskeletal disorders · 2025Article
- Larger nail-shaft gap as a potential risk factor of femoral head varus in patients treated with proximal femoral nail antirotation fixation: a retrospective, observational, single-center study with corresponding numerical simulation.Quantitative imaging in medicine and surgery · 2025Article
- Article
- Comparative Analysis of Three Vertebral Screw Placement Directions in Anterior Thoracolumbar Fracture Surgery: A Finite Element Study.Orthopaedic surgery · 2025Article
- Is lumbar spondylolisthesis a risk factor of cage subsidence after oblique lumbar interbody fusion combined with anterolateral screw fixation?Journal of orthopaedic surgery and research · 2025Article
- An OLIF Cage Integrated with a Low-Profile Plate and Cross Screws Could Reduce the Risk of Postoperative Complications Biomechanically.Annals of biomedical engineering · 2025Article
- Article
- The Bony Density of the Pedicle Plays a More Significant Role in the Screw Anchorage Ability Than Other Regions of the Screw Trajectory.Orthopaedic surgery · 2025Article
- The ratio between the screw distance and femoral neck width on lateral radiography is a reliable predictor of femoral head necrosis: a clinical review and corresponding numerical simulations.Journal of orthopaedic surgery and research · 2024Article
- Tomographic Assessment of Fusion Rate, Implant-Endplate Contact Area, Subsidence, and Alignment With Lumbar Personalized Interbody Implants at 1-Year Follow-Up.International journal of spine surgery · 2024Article
- Impact of screw tip design on screw anchorage: mechanical testing and numerical simulation.Journal of orthopaedic surgery and research · 2024Article
- Changes in nail position and antirotation blade angles on the risk of femoral head varus in PFNA fixed patients: a clinical review and comprehensive biomechanical research.European journal of medical research · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mismatch between bony endplates (BEPs) and grafted bone (GB) triggers several complications biomechanically. However, no published study has identified whether this factor increases the risk of screw loosening by deteriorating the local stress levels. This study aimed to illustrate the biomechanical effects of the mismatch between BEP and GB and the related risk of screw loosening. In this study, radiographic and demographic data of 56 patients treated by single segment oblique lumbar interbody fusion (OLIF) with anterior lateral single rod (ALSR) fixation were collected retrospectively, and the match sufficiency between BEP and GB was measured and presented as the grafted bony occupancy rate (GBOR). Data in patients with and without screw loosening were compared; regression analyses identified independent risk factors. OLIF with different GBORs was simulated in a previously constructed and validated lumbosacral model, and biomechanical indicators related to screw loosening were computed in surgical models. The radiographic review and numerical simulations showed that the coronal plane's GBOR was significantly lower in screw loosening patients both in the cranial and caudal vertebral bodies; the decrease in the coronal plane's GBOR has been proven to be an independent risk factor for screw loosening. In addition, numerical mechanical simulations showed that the poor match between BEP and GB will lead to stress concentration on both screws and bone-screw interfaces. Therefore, we can conclude that the mismatch between the BEP and GB will increase the risk of screw loosening by deteriorating local stress levels, and the increase in the GBOR by modifying the OLIF cage's design may be an effective method to optimize the patient's prognosis.
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