Evidence map›Paper›PMID 35464686›Full record

ArticleAmerican journal of ophthalmology case reports2022

Hydralazine-induced vasculitis presenting with ocular manifestations.

Vivian S Hawn, Thomas A Vo, David Flomenbaum, Richard P Gibralter

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vivian S HawnAlbert Einstein College of Medicine, 1300 Morris Park Avenue, NY, 10461, Bronx, USA.
Thomas A VoDepartment of Ophthalmology and Visual Sciences, Montefiore Medical Center, 111 East 210th Street, NY, 10467, Bronx, USA.
David FlomenbaumAlbert Einstein College of Medicine, 1300 Morris Park Avenue, NY, 10461, Bronx, USA.
Richard P GibralterDepartment of Ophthalmology and Visual Sciences, Montefiore Medical Center, 111 East 210th Street, NY, 10467, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The objective of the study is to report a case of ocular manifestations in a patient with hydralazine-induced vasculitis. Observations: An 88-year-old female was admitted for lower gastrointestinal bleeding. Nine days after admission, she developed bilateral conjunctival chemosis and injection, which rapidly progressed into grouped blistering eruptions of the periorbital skin, face, and neck. After extensive testing and evaluation, her constellation of findings was diagnosed as hydralazine-induced vasculitis. Treatment with intravenous steroids and discontinuation of hydralazine resulted in improvement of the cutaneous and ocular manifestations. Herein we describe the clinical course of an adult patient with symptoms and signs consistent with hydralazine-induced vasculitis to highlight that ophthalmological manifestations can be the first symptoms in patients with life-threatening dermatological conditions. Conclusions and Importance: To our knowledge, this report is the first case of hydralazine-induced vasculitis initially presenting with ocular manifestations.

Indexed as

ANA, Anti-nuclear antibodiesc-ANCA, cytoplasmic antineutrophil cytoplasmic antibodyConjunctival chemosisConjunctival injectionDIV, Drug-induced vasculitisHSV, Herpes simplex virusHydralazinep-ANCA, perinuclear antineutrophil cytoplasmic antibodyVasculitis

Identifiers

PMID35464686
PMCPMC9020102

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.