Evidence map›Paper›PMID 35464671›Full record

ArticleNuclear medicine and molecular imaging2022

[68 Ga]Ga-PSMA-11 Small Bowel Uptake in Crohn's Disease: Revisiting the "Non-specificity" of PSMA Ligands.

Kunal Ramesh Chandekar, Sindhu Tanigassalam, Anwin Joseph Kavanal, Harmandeep Singh, Anish Bhattacharya, Ravimohan Suryanarayan Mavuduru

Abstract readCase Reports
In one paragraph

Article in Nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Targeting glutamate carboxypeptidase II in IBD.Advances in pharmacology (San Diego, Calif.) · 2024
    Review
  3. PSMA-Targeted PET Radiotracer [Clinical and experimental gastroenterology · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kunal Ramesh ChandekarDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Sindhu TanigassalamDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Anwin Joseph KavanalDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Harmandeep SinghDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.ORCID 0000-0002-1472-104X
Anish BhattacharyaDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.
Ravimohan Suryanarayan MavuduruDepartment of Urology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapidly evolving clinical utility of prostate-specific membrane antigen (PSMA) PET/CT as an imaging modality for prostate cancer (PCa) has brought to the forefront a multitude of non-prostatic diseases also exhibiting PSMA radioligand uptake. We report a case of a 71-year-old male with PCa who underwent PSMA PET/CT for recurrence evaluation. The scan demonstrated [68 Ga]Ga-PSMA-11 uptake in the distal ileum. Retrospective enquiry revealed that the patient was a known case of Crohn's disease. This case highlights an uncommon finding of PSMA radioligand uptake in the distal small bowel (non-prostatic benign pathological uptake) in a patient with known Crohn's disease, which may be misinterpreted in the evaluation of PCa.

Indexed as

Crohn’s diseaseInflammatory bowel disease (IBD)PET/CTProstate cancerProstate-specific membrane antigen (PSMA)

Identifiers

PMID35464671
PMCPMC8976716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.