ArticleJournal of clinical medicine research2022
Population Status of Iodine and Its Potential Effects on Thyroid Function and Autoimmunity in Southwestern Colombia.
Article in Journal of clinical medicine research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of iodine nutritional status on the recurrence of hyperthyroidism and antithyroid drug efficacy in adult patients with Graves' disease: a systemic review.Frontiers in endocrinology · 2023Pooled it
- Iodine Intake from Universal Salt Iodization Programs and Hashimoto's Thyroiditis: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- Zinc and Ferritin Levels and Their Associations with Functional Disorders and/or Thyroid Autoimmunity: A Population-Based Case-Control Study.International journal of molecular sciences · 2024Article
- Study on the Relationship Between Serum Iodine and Thyroid Dysfunctions: a Cross-Sectional Study.Biological trace element research · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to investigate the iodine status and its potential effects on thyroid function and autoimmunity in Colombia. Methods: This was a cross-sectional study, in population of urban and rural areas, from four geographic regions in the Department of Cauca, Colombia; the participants were 412 healthy adults, a third from rural areas. The following variables were evaluated: median urinary iodine concentration (mUIC), serum thyrotropin (TSH), clinical and ultrasonographic (US) goiter assessment, and anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-Tg) and anti-TSH receptor (TRAb) concentrations. Results: The mUIC levels were 153.9 µg/L (interquartile range (IQR): 220.06); 30% had "excessive" mUIC and a quarter had "low" mUIC. The positivity of anti-Tg and anti-TPO was higher in subjects > 60 years (P = 0.017 and P ≤ 0.001, respectively). A high prevalence of "low" mUIC was found in the "low" socioeconomic status (SES) and of "more than adequate or excessive" in the "high" SES when compared with the "medium" SES (P ≤ 0.001). The prevalence of goiter by physical examination was 41.7% and 34% by US. The highest mUIC levels were significantly more prevalent in women, in subjects with elevated TSH and in those from rural areas. Conclusions: The population status of iodine in Colombia is U-shaped; the high prevalence of goiter, hypothyroidism, and thyroid autoimmunity can be explained by excess or deficit of iodine and by probable environmental goitrogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.