Evidence map›Paper›PMID 35464606›Full record

ArticleJournal of clinical medicine research2022

Acute Promyelocytic Leukemia in a Patient With Chronic Continuous Type of Crohn's Disease.

Shiori Kinoshita, Satoshi Tanida, Akimi Kawai, Kazuhide Shiraga, Tomoyuki Nakamura, Kana Oiwa, Tomotaka Suzuki, Asahi Ito, Masaki Ri, Shigeru Kusumoto and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shiori KinoshitaDepartment of Hematology, Toyokawa City Hospital, Toyokawa City, Aichi Prefecture, Japan.
Satoshi TanidaDepartment of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Akimi KawaiDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Kazuhide ShiragaDepartment of Hematology, Toyokawa City Hospital, Toyokawa City, Aichi Prefecture, Japan.
Tomoyuki NakamuraDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Kana OiwaDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Tomotaka SuzukiDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Asahi ItoDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Masaki RiDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Shigeru KusumotoDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Hirokazu KomatsuDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.
Shinsuke IidaDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi Prefecture, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inflammation can induce leukemogenic mutations in hematopoietic stem cells (HSCs). We report a case of acute promyelocytic leukemia (APL) in a patient with chronic continuous type of Crohn's disease. The patient had been diagnosed with Crohn's disease at the age of 28 years and had received conventional treatments with biologics, but not azathioprine. At the age of 51, he was diagnosed with APL with ider(17). Long-term exposure to chronic continuous inflammation from Crohn's disease might be a factor inducing genomic instability in HSCs, which lead to the subsequent development of APL. APL is a rare hematological manifestation that required attention in Crohn's disease patients.

Indexed as

Acute promyelocytic leukemiaChronic inflammationCrohn’s diseaseHematopoietic stem cellInflammatory bowel diseaseMyeloid neoplasm

Identifiers

PMID35464606
PMCPMC8993430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.