Evidence map›Paper›PMID 35464549›Full record

ArticleCureus2022

Relationship Between Marijuana Use and Hospitalization for Acute Coronary Syndrome.

Niraj Karki, Binita Sapkota, Swosti R Magar, Ameen Muhammad, Bishow M Paudel, Peter Chernek, Maryam Afshar, Manoj Bhandari, Jonathan N Bella

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Niraj KarkiInternal Medicine, Catholic Health Initiatives (CHI) St. Vincent, Little Rock, USA.
Binita SapkotaRheumatology/Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Swosti R MagarInternal Medicine/Rheumatology, University of Arkansas for Medical Sciences, Little Rock, USA.
Ameen MuhammadInternal Medicine, BronxCare Health System, Bronx, USA.
Bishow M PaudelInternal Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA.
Peter ChernekInternal Medicine, BronxCare Health System, Bronx, USA.
Maryam AfsharInternal Medicine/Cardiology, BronxCare Health System, Bronx, USA.
Manoj BhandariCardiology, Cape Fear Valley Health System, Fayetteville, USA.
Jonathan N BellaInternal Medicine/Cardiology, BronxCare Health System, Bronx, USA.
MemorialCare Health System · USUniversity of Arkansas for Medical Sciences · USCape Fear Valley Health System · USCHI St. Vincent · USUniversity of Iowa Hospitals and Clinics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecreational marijuana use is rising, especially among young adults. The cardiovascular (CVD) effect of marijuana remains mostly unknown.

methodsThis is a retrospective study of 14,490 patients admitted to our hospital between 2012 and 2014 who had urine toxicology done for various reasons. Patients with a primary diagnosis of acute coronary syndrome (ACS) were queried in both the marijuana-positive group (n = 59) and the marijuana-negative group (n = 195). The risks of having ACS were compared in both groups.

resultsThere was no difference in the risk of having ACS between the two groups in the population < 54 years of age (OR: 0.90, 95% CI: 0.67-1.20, p = 0.48). However, there was a significant difference in the risk of having ACS in the 18-36 age group (OR: 2.84, 95% CI: 1.14-7.07, p = 0.01). Multivariate analysis performed to adjust for the potential confounding effects of smoking and cocaine use showed that marijuana use (OR: 0.93, 95% CI: 0.68-1.25, p = 0.65) did not increase the likelihood of ACS for patients ≤ 54 years or for those in the 37-54 age group (OR: 1.11, 95% CI: 0.79-1.53, p = 0.50). However, among the 18-36 age bracket, marijuana use was independently associated with a higher risk of ACS (OR: 5.24, 95% CI: 1.84-16.93, p = 0.002).

conclusionIn younger patients (age 18-36 years), marijuana use is independently associated with a five-fold higher risk of ACS.

Indexed as

acute coronary syndromecardiovascular effectsmarijuanamarijuana use and hospitalizationurine toxicology

Identifiers

PMID35464549
PMCPMC9014837
OpenAlexW4220742030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.