Evidence map›Paper›PMID 35464486›Full record

ReviewFrontiers in immunology2022

Biology and Clinical Relevance of HCMV-Associated Adaptive NK Cells.

Fei Gao, Zhengwei Zhou, Ying Lin, Guang Shu, Gang Yin, Tianxiang Zhang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. The immune response to human cytomegalovirus: impact of age, co-morbidities and the significance of anti-viral activity assessment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Nutrient transporter pattern in CD56Frontiers in immunology · 2024
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fei GaoImmuno-Oncology Laboratory, Department of Pathology, School of Basic Medicine, Central South University, Changsha, China.
Zhengwei ZhouImmuno-Oncology Laboratory, Department of Pathology, School of Basic Medicine, Central South University, Changsha, China.
Ying LinImmuno-Oncology Laboratory, Department of Pathology, School of Basic Medicine, Central South University, Changsha, China.
Guang ShuImmuno-Oncology Laboratory, Department of Pathology, School of Basic Medicine, Central South University, Changsha, China.
Gang YinImmuno-Oncology Laboratory, Department of Pathology, School of Basic Medicine, Central South University, Changsha, China.
Tianxiang ZhangDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are an important component of the innate immune system due to their strong ability to kill virally infected or transformed cells without prior exposure to the antigen (Ag). However, the biology of human NK (hNK) cells has largely remained elusive. Recent advances have characterized several novel hNK subsets. Among them, adaptive NK cells demonstrate an intriguing specialized antibody (Ab)-dependent response and several adaptive immune features. Most adaptive NK cells express a higher level of NKG2C but lack an intracellular signaling adaptor, FcϵRIγ (hereafter abbreviated as FcRγ). The specific expression pattern of these genes, with other signature genes, is the result of a specific epigenetic modification. The expansion of adaptive NK cells

Indexed as

CytomegalovirusCytomegalovirus InfectionsBiologyHumansKiller Cells, NaturalLeukocytes, Mononuclearadaptive NK cellsADCCepigenetic remodelingHCMVtherapeutic potential

Identifiers

PMID35464486
PMCPMC9022632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.