Evidence map›Paper›PMID 35464468›Full record

ArticleFrontiers in immunology2022

Co-Expression of the B-Cell Key Transcription Factors Blimp-1 and IRF4 Identifies Plasma Cells in the Pig.

Sonia Villanueva-Hernández, Mahsa Adib Razavi, Katinka A van Dongen, Maria Stadler, Karelle de Luca, Niklas Beyersdorf, Armin Saalmüller, Wilhelm Gerner, Kerstin H Mair

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Sonia Villanueva-HernándezChristian Doppler (CD) Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Mahsa Adib RazaviChristian Doppler (CD) Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Katinka A van DongenChristian Doppler (CD) Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Maria StadlerInstitute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Karelle de LucaLaboratory of Veterinary Immunology, Global Innovation, Boehringer Ingelheim Animal Health, Lyon, France.
Niklas BeyersdorfInstitute for Virology and Immunobiology, Julius-Maximilians-University, Würzburg, Germany.
Armin SaalmüllerInstitute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Wilhelm GernerChristian Doppler (CD) Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Kerstin H MairChristian Doppler (CD) Laboratory for Optimized Prediction of Vaccination Success in Pigs, Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
University of Veterinary Medicine Vienna · ATBoehringer Ingelheim (France) · FRUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-secreting plasma cells (PCs) have remained largely uncharacterized for years in the field of porcine immunology. For an in-depth study of porcine PCs, we identified cross-reactive antibodies against three key transcription factors: PR domain zinc finger protein-1 (Blimp-1), interferon regulatory factor 4 (IRF4), and paired box 5 (Pax5). A distinct Blimp-1

Indexed as

CD28 AntigensPlasma CellsAnimalsCell DifferentiationImmunoglobulin AImmunoglobulin GImmunoglobulin MInterferon Regulatory FactorsKi-67 AntigenMicePAX5 Transcription FactorSwineCD28 AntigensImmunoglobulin AImmunoglobulin GImmunoglobulin MInterferon Regulatory FactorsKi-67 AntigenPAX5 Transcription FactorBLIMP-1immunoglobulin classesIRF4pigplasma cells

Identifiers

PMID35464468
PMCPMC9024106
OpenAlexW4226048788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.