Evidence map›Paper›PMID 35464451›Full record

ReviewFrontiers in immunology2022

The Role of NcRNAs to Regulate Immune Checkpoints in Cancer.

Yicun Jiang, Leilei Zhao, Yiwen Wu, Sijun Deng, Pu Cao, Xiaoyong Lei, Xiaoyan Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yicun JiangSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Leilei ZhaoSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Yiwen WuSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Sijun DengSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Pu CaoSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Xiaoyong LeiSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
Xiaoyan YangSchool of Pharmacy, Hengyang Medical College, University of South China, Hengyang, China.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, the incidence of cancer is becoming more and more common, but its treatment has always been a problem. Although a small number of cancers can be treated, the recurrence rates are generally high and cannot be completely cured. At present, conventional cancer therapies mainly include chemotherapy and radiotherapy, which are the first-line therapies for most cancer patients, but there are palliatives. Approaches to cancer treatment are not as fast as cancer development. The current cancer treatments have not been effective in stopping the development of cancer, and cancer treatment needs to be imported into new strategies. Non-coding RNAs (ncRNAs) is a hot research topic at present. NcRNAs, which include microRNAs (miRNAs), circular RNAs (circRNAs), and long non-coding RNAs (lncRNAs), participate in all aspects of cancer biology. They are involved in the progression of tumors into a new form, including B-cell lymphoma, glioma, or the parenchymal tumors such as gastric cancer and colon cancer, among others. NcRNAs target various immune checkpoints to affect tumor proliferation, differentiation, and development. This might represent a new strategy for cancer treatment.

Indexed as

MicroRNAsNeoplasmsRNA, Long NoncodingHumansRNA, CircularRNA, UntranslatedMicroRNAsRNA, CircularRNA, Long NoncodingRNA, UntranslatedcancercircRNAimmune checkpointslncRNAmiRNA

Identifiers

PMID35464451
PMCPMC9019622
OpenAlexW4225627410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.