Evidence map›Paper›PMID 35464448›Full record

ArticleFrontiers in immunology2022

Identification of the Transgene Integration Site and Host Genome Changes in MRP8-Cre/ires-EGFP Transgenic Mice by Targeted Locus Amplification.

Guan Wang, Cunling Zhang, Hiroto Kambara, Cheryl Dambrot, Xuemei Xie, Li Zhao, Rong Xu, Andrea Oneglia, Fei Liu, Hongbo R Luo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Transgene Mapping in Animals: What to Choose?International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Comprehensive analysis of myeloid reporter mice.bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Guan WangDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Cunling ZhangThe State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Hiroto KambaraDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Cheryl DambrotCergentis BV, Utrecht, Netherlands.
Xuemei XieDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Li ZhaoDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Rong XuDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Andrea OnegliaCergentis BV, Utrecht, Netherlands.
Fei LiuThe State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Hongbo R LuoDepartment of Pathology, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, MA, United States.
Dana-Farber/Harvard Cancer Center · USCergentis (Netherlands) · NLBoston Children's Hospital · USChinese Academy of Medical Sciences & Peking Union Medical College · CNInstitute of Hematology & Blood Diseases Hospital · CN

Funding

Novel Strategies to Improve Blood Transfusion PracticeP01HL158688 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Hongbo R Luo · 2022 to 2026
$12.9M
NHLBI NIH HHS P01 HL158688
6 · The paper itself

Abstract

The MRP8-Cre-ires/EGFP transgenic mouse (Mrp8cre

Indexed as

IntegrasesInternal Ribosome Entry SitesAnimalsMiceMice, Inbred C57BLMice, TransgenicTransgenesCre recombinaseIntegrasesInternal Ribosome Entry SitesCre-loxP systemhomozygous lethalityMRP8-Cre transgenic mouseneutrophilTLA sequencing

Identifiers

PMID35464448
PMCPMC9020256
OpenAlexW4225999919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.