Evidence map›Paper›PMID 35464411›Full record

ArticleFrontiers in immunology2022

Large-Scale Single-Cell and Bulk Sequencing Analyses Reveal the Prognostic Value and Immune Aspects of CD147 in Pan-Cancer.

Jingwei Zhang, Zeyu Wang, Xun Zhang, Ziyu Dai, Wen Zhi-Peng, Jing Yu, Yun Peng, Wantao Wu, Nan Zhang, Peng Luo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer.European journal of nuclear medicine and molecular imaging · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Acta pharmacologica Sinica · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Jingwei ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Zeyu WangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Xun ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Ziyu DaiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Wen Zhi-PengDepartment of Pharmacy, The Affiliated Hospital of Guizhou Medical University, Guizhou Medical University, Guiyang, China.
Jing YuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yun PengDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.
Wantao WuDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, China.
Nan ZhangOne-third Lab, College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Peng LuoDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Jian ZhangDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Zaoqu LiuDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou, Zhengzhou, China.
Songshan FengDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Hao ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Quan ChengDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CNAffiliated Hospital of Guizhou Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CNHarbin Medical University · CNSouthern Medical University · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD147 plays an important role in promoting tumor proliferation and inhibiting cancer cell apoptosis in the tumor microenvironment. However, the mechanisms by which CD147 is involved in tumorigenesis remains unclear. This study systematically analyzed the prognostic value and immune characteristics of CD147 in 31 cancer types. The expression levels and mutant landscapes of CD147 in pan-cancer were explored. The Kaplan-Meier (KM) analysis was applied to analyze the prognostic value of CD147. The immune characteristics of CD147 in the tumor microenvironment were evaluated

Indexed as

NeoplasmsTumor MicroenvironmentHumansImmune Checkpoint ProteinsImmunotherapyPrognosisImmune Checkpoint ProteinsCD147immunotherapymacrophagespan-cancertumor microenvironment

Identifiers

PMID35464411
PMCPMC9019465
OpenAlexW4225434095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.