Evidence map›Paper›PMID 35464397›Full record

ReviewFrontiers in immunology2022

Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives.

Elaine Dempsey, Sinéad C Corr

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07144475 (Comparison of Probiotic Effects of Lactobacillus Casei Shirota With Lactobacillus Acidophilus on the Outcomes of Patients After Colorectal Cancer Surgery), which is not on this map. Cited by 285 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
285citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07144475 phase4completednot on this mapstarted 2024, after this paper: background citation

Comparison of Probiotic Effects of Lactobacillus Casei Shirota With Lactobacillus Acidophilus on the Outcomes of Patients After Colorectal Cancer Surgery: A Study of Gastrointestinal Function, Sepsis Incidence, C-Reactive Protein, Interleukin 6 and Length of Stay

TypeinterventionalSponsorDharmais National Cancer Center HospitalRan2024 to 2025Enrolled90ConditionsColorectal CancerArmsLactobacillus casei Shirota, Lactobacillus acidophilus
3 · Its place in the literature

Who cites it

285 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Effect of AG1Frontiers in nutrition · 2026
    Trial
  11. Trial
  12. Trial
  13. Review
  14. Virulence · 2026
    Article
  15. Nutrients · 2026
    Article
  16. Kernel Fatty Oils ofNutrients · 2026
    Article
  17. Article
  18. Article
  19. ProbioticCells · 2026
    Article
  20. Article

225 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elaine DempseyTrinity Biomedical Science Institute, School of Biochemistry and Immunology, Trinity College, Dublin, Ireland.
Sinéad C CorrDepartment of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, probiotic bacteria have become increasingly popular as a result of mounting scientific evidence to indicate their beneficial role in modulating human health. Although there is strong evidence associating various Lactobacillus probiotics to various health benefits, further research is needed, in particular to determine the various mechanisms by which probiotics may exert these effects and indeed to gauge inter-individual value one can expect from consuming these products. One must take into consideration the differences in individual and combination strains, and conditions which create difficulty in making direct comparisons. The aim of this paper is to review the current understanding of the means by which Lactobacillus species stand to benefit our gastrointestinal health.

Indexed as

LactobacillusProbioticsBacteriaGastrointestinal TractHumansgastrointestinal barrierinflammationlactobacillusmicrobiotaprobiotic

Identifiers

PMID35464397
PMCPMC9019120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.