Evidence map›Paper›PMID 35464331›Full record

ArticleJournal of medical cases2022

COVID-19 Presenting With a Challenging Combination of Thrombocytopenia and Thrombosis.

Swapna Ravi, Sushmita Khadka, Charumathi Subrahmanian Raghu, Ananth Ravi, Sharmisha Vanukuri, Tapasya Mandalapu, Vineela Kasireddy

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Swapna RaviDepartment of Internal Medicine, St. Luke's Internal Medicine Associates, Duluth, MN, USA.
Sushmita KhadkaDepartment of Internal Medicine, Guthrie Clinic/Robert Packer Hospital, Sayre, PA, USA.
Charumathi Subrahmanian RaghuDepartment of Medicine, Washington Hospital Health Care System, Fremont, CA, USA.
Ananth RaviDepartment of Radiology, Essentia Health-St. Mary's Medical Center, Duluth, MN, USA.
Sharmisha VanukuriDepartment of Medicine, Miami University, Miami, FL, USA.
Tapasya MandalapuDepartment of Medicine, HCA Houston Healthcare Conroe, Houston, TX, USA.
Vineela KasireddyDepartment of Hematology and Oncology, Guthrie Clinic/Robert Packer Hospital, Sayre, PA, USA.
Guthrie Robert Packer Hospital · USEssentia Health · USHouston Health and Human Services Department · USSt. Luke's Clinic · USUniversity of Miami · USWashington Hospital Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) causes various hematological abnormalities, leading to several complications in the disease course. We report two COVID-19 cases presenting with a combination of thrombocytopenia and coagulopathy complications in late 2020. A 73-year-old male with a history of immune thrombocytopenic purpura (ITP) presented with acute ischemic stroke and acute thrombocytopenia in the setting of COVID-19. He was managed with steroids and intravenous immunoglobulin (IVIG) and had a subsequent acute ischemic stroke with microhemorrhages. Another 72-year-old female with a history of cryptogenic liver cirrhosis and chronic thrombocytopenia presenting with acute thrombocytopenia in the setting of COVID-19 was managed with steroids and IVIG. She had a coagulopathic complication of deep venous thrombosis (DVT) later in her disease course managed with inferior vena cava filter and low-dose enoxaparin, but she subsequently died with a bleeding complication of retroperitoneal hemorrhage. Despite the aggressive ongoing research, the treatment options for severe COVID-19 are limited to date and the mortality remains high. Both these cases are examples of challenging situations that the physicians are currently facing with COVID-19 pandemic.

Indexed as

CoagulopathyCOVID-19ThrombocytopeniaThrombosis

Identifiers

PMID35464331
PMCPMC8993441
OpenAlexW4220787901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.