Evidence map›Paper›PMID 35464224›Full record

ReviewFrontiers in chemistry2022

Graphene-Based Electrochemical Sensor for Detection of Hepatocellular Carcinoma Markers.

Ying Liang, Yuan Xu, Yaoyao Tong, Yue Chen, Xilu Chen, Shimin Wu

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ying LiangCenter for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, China.
Yuan XuCenter for Clinical Laboratory, Wuhan Hospital of Chinese Medicine, Wuhan, China.
Yaoyao TongCenter for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, China.
Yue ChenCenter for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, China.
Xilu ChenCenter for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, China.
Shimin WuCenter for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, China.
Yangtze Optical Electronic (China) · CNWuhan City Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a group of highly lethal malignant tumors that seriously threaten human health. The main way to improve the survival quality and reduce the mortality of HCC is early diagnosis and treatment. Therefore, it will be of great significance to explore new quantitative detection methods for HCC markers. With the rapid development of electrochemical biosensors and nanomaterials, electrochemical sensors based on graphene can detect tumor markers, with the advantages of simple operation, high detection sensitivity, and specificity. Combined with the published literature in recent years, the article briefly reviews the application of graphene-based electrochemical biosensors in the detection of HCC markers, including alpha-fetoprotein (AFP), Golgi protein-73 (GP73), exosomes, and microRNA-122 (miR-122).

Indexed as

electrochemical sensorgraphenehepatocellular carcinomananometer materialtumor markers

Identifiers

PMID35464224
PMCPMC9024117
OpenAlexW4225968655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.