Evidence map›Paper›PMID 35464218›Full record

ArticleFrontiers in chemistry2022

Mucin-Type

YashoNandini Singh, Deepika Regmi, David Ormaza, Ramya Ayyalasomayajula, Nancy Vela, Gustavo Mundim, Deguo Du, Dmitriy Minond, Maré Cudic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Implications of Mucin-TypeMolecules (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

YashoNandini SinghDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Deepika RegmiDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
David OrmazaDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Ramya AyyalasomayajulaDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Nancy VelaDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Gustavo MundimDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Deguo DuDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Dmitriy MinondCollege of Pharmacy and Rumbaugh-Goodwin Institute for Cancer Research, Nova Southeastern University, Fort Lauderdale, FL, United States.
Maré CudicDepartment of Chemistry and Biochemistry, Charles E. Schmidt College of Science, Florida Atlantic University, Boca Raton, FL, United States.
Florida Atlantic University · USNova Southeastern University · US

Funding

Mechanistic insight into tumor-associated MUC1 glycopeptides binding to macrophage galactose-type lectinR15CA242351 · NCI · FLORIDA ATLANTIC UNIVERSITY · PI CUDIC, MARE · 2019 to 2024
$878k
Role of the N-terminal Region in Abeta Oligomer and Fibril FormationR15GM116006 · NIGMS · FLORIDA ATLANTIC UNIVERSITY · PI DU, DEGUO · 2015 to 2020
$735k
NCI NIH HHS R15 CA242351NIGMS NIH HHS R15 GM116006
6 · The paper itself

Abstract

The amyloid-β precursor protein (APP) undergoes proteolysis by β- and γ-secretases to form amyloid-β peptides (Aβ), which is a hallmark of Alzheimer's disease (AD). Recent findings suggest a possible role of

Indexed as

aggregation kineticsAlzheimer’s diseaseAPP O-glycopeptidescircular dichroismproteolysis

Identifiers

PMID35464218
PMCPMC9023740
OpenAlexW4225609275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.