Evidence map›Paper›PMID 35464185›Full record

ArticleNeurobiology of pain (Cambridge, Mass.)

Gut microbiota and migraine.

Joshua Crawford, Sufang Liu, Feng Tao

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of pain (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  17. Article
  18. Migraine Comorbidities.Life (Basel, Switzerland) · 2024
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joshua CrawfordDepartment of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
Sufang LiuDepartment of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
Feng TaoDepartment of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
Texas A&M University · US

Funding

A new animal model for stress-induced transition from acute to chronic painK02DE023551 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI TAO, FENG · 2014 to 2018
$564k
Targeting Gut-Brain Axis Signaling to Treat Opioid Induced Hyperalgesia and Tolerance in Mice with Chronic Trigeminal Neuropathic PainF31DE029686 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI CRAWFORD, JOSHUA A. · 2020 to 2023
$145k
NIDCR NIH HHS F31 DE029686NIDCR NIH HHS K02 DE023551
6 · The paper itself

Abstract

Migraine is a leading cause of disability among the adult population and is a significant burden on the economies of the world. Studies into the underlying causes of migraine have spanned centuries but its underlying mechanisms are still not fully understood. In recent years, accumulating evidence implicates that microbiota-mediated gut-brain crosstalk may contribute to the pathogenesis of migraine. This review provides a brief account of the history of migraine theories and summarizes the recent studies showing how gut microbiota is involved in the pathophysiology of migraine. Future research perspectives for better understanding the role of the gut microbiota in migraine are also discussed.

Indexed as

Gut microbiotaMigraineProbioticsShort-chain fatty acidsVagus nerve

Identifiers

PMID35464185
PMCPMC9018445
OpenAlexW4224859081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.