ArticleBrain hemorrhages2023
Pituitary apoplexy following adenoviral vector-based COVID-19 vaccination.
Article in Brain hemorrhages, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- COVID19 infection and vaccination and the risk of pituitary apoplexy: an entangled yarn.Endocrine · 2025Pooled it
- Pituitary and COVID-19 vaccination: a systematic review.Pituitary · 2024Pooled it
- Endocrine system after 2 years of COVID-19 vaccines: A narrative review of the literature.Frontiers in endocrinology · 2022Pooled it
- Pituitary Apoplexy in a Child with Short Stature and Possible Recent SARS-CoV-2 Infection.Diagnostics (Basel, Switzerland) · 2025Article
- Pituitary Apoplexy: a re-appraisal of risk factors and best management strategies in the COVID-19 era.Pituitary · 2024Review
- Review
- Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report.BMC endocrine disorders · 2024Article
- Rapid expansion of a left atrial myxoma caused by acute multiple internal hemorrhages: a case report and literature review.Journal of cardiothoracic surgery · 2024Review
- Article
- Pituitary and SARS CoV-2: An unremitting conundrum.Best practice & research. Clinical endocrinology & metabolism · 2023Review
- Central diabetes insipidus: a late sequela of BNT162b2 SARS-CoV-2 mRNA vaccine?BMC endocrine disorders · 2023Article
- Post-COVID-19 Vaccination CNS Magnetic Resonance Imaging Findings: A Systematic Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Review
- Evidences that SARS-CoV-2 Vaccine-Induced apoplexy may not be solely due to ASIA or VITT syndrome', Commentary on Pituitary apoplexy and COVID-19 vaccination: A case report and literature review.Frontiers in endocrinology · 2023Article
- AVP deficiency (central diabetes insipidus) following immunization with anti-COVID-19 BNT162b2 Comirnaty vaccine in adolescents: A case report.Frontiers in endocrinology · 2023Article
- Pilot Findings on SARS-CoV-2 Vaccine-Induced Pituitary Diseases: A Mini Review from Diagnosis to Pathophysiology.Vaccines · 2022Review
- Apropos of menstrual changes and abnormal uterine bleeding after COVID-19 vaccination.Brain hemorrhages · 2022Article
- Spot the adenoma after pituitary apoplexy following a SARS-CoV-2 vaccination.Brain hemorrhages · 2022Article
- Revisiting Pituitary Apoplexy.Journal of the Endocrine Society · 2022Review
- Pituitary apoplexy and COVID-19 vaccination: a case report and literature review.Frontiers in endocrinology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pituitary apoplexy (PA) may complicate the course of coronavirus disease 2019 (COVID-19), posing a potential threat to life. Among vaccines designed to prevent COVID-19, there are those adenoviral vector-based, such as Vaxzevria® (formerly COVID-19 Vaccine AstraZeneca). The product insert states that it can cause very rare coagulation disorders, in particular thrombosis with thrombocytopenia syndrome in some cases accompanied by bleeding, cerebrovascular venous or sinus thrombosis, and thrombocytopenia, including immune thrombocytopenia, also associated with bleeding. Here, we report the onset of PA after Vaxzevria® in a 28-year-old healthy Caucasian female, who experienced long-lasting tension-type headache, hyperprolactinemia and menstrual changes, without thrombocytopenia or thrombosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.