ArticleACS catalysis2021
Catalytic Arylboration of Spirocyclic Cyclobutenes: Rapid Access to Highly Substituted Spiro[3.n]alkanes.
Article in ACS catalysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Enantioselective Synthesis of 2,3-Disubstituted Azetidines via Copper-Catalyzed Boryl Allylation of Azetines.Journal of the American Chemical Society · 2025Article
- Approach Toward Stereoselective α-Arylation by Pd/Cu-Catalyzed Arylboration of Electron Deficient Alkenes.Angewandte Chemie (International ed. in English) · 2025Article
- Stereoselective polar radical crossover for the functionalization of strained-ring systems.Communications chemistry · 2024Article
- Organophosphates as Versatile Substrates in Organic Synthesis.Molecules (Basel, Switzerland) · 2024Review
- Borylated cyclobutanesChemical science · 2024Article
- Synthesis of (±)-Phyltetralin by Cu/Pd-Catalyzed Arylboration.Synlett : accounts and rapid communications in synthetic organic chemistry · 2023Article
- Cu/Pd-catalyzed arylboration of a 1-silyl-1,3-cyclohexadiene for stereocontrolled and diverse cyclohexane/ene synthesis.Chemical science · 2023Article
- 2-Oxabicyclo[2.1.1]hexanes as saturated bioisosteres of the ortho-substituted phenyl ring.Nature chemistry · 2023Article
- Catalytic Dienylation: An Emergent Strategy for the Stereoselective Construction of Conjugated Dienes and Polyenes.Synthesis · 2023Article
- Synthesis of 3-borylated cyclobutanols from epihalohydrins or epoxy alcohol derivatives.Chemical science · 2023Article
- Arylboration of Enecarbamates for the Synthesis of Borylated Saturated N-Heterocycles.Angewandte Chemie (International ed. in English) · 2022Article
- Boosting the Enantioselectivity of Conjugate Borylation of α,β-Disubstituted Cyclobutenones with Monooxides of Chiral CChemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Photosensitized [2+2]-Cycloadditions of Alkenylboronates and Alkenes.Angewandte Chemie (International ed. in English) · 2022Article
- A stereochemical journey around spirocyclic glutamic acid analogs.Organic & biomolecular chemistry · 2022Article
- Cooperative Pd/Cu Catalysis for Alkene Arylboration: Opportunities for Divergent Reactivity.ACS catalysis · 2022Article
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3 authors.
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Abstract
A method to achieve the synthesis of highly substituted spirocyclic cyclobutanes is disclosed. The reaction involves the catalytic arylboration of cyclobutenes. Depending on the substitution pattern of the cyclobutene, either a Cu/Pd- or a Ni-catalyzed reaction was utilized. In the case of the Cu/Pd catalyzed reactions, the identification of a Cu-complex for arylboration was crucial to observe high selectivity. The synthetic utility of the products is demonstrated, and the mechanistic details are discussed.
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