Evidence map›Paper›PMID 35464068›Full record

ArticleFrontiers in endocrinology2022

Expressions of Serum lncRNAs in Diabetic Retinopathy - A Potential Diagnostic Tool.

Saumik Biswas, Ali Coyle, Shali Chen, Miso Gostimir, John Gonder, Subrata Chakrabarti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Long Noncoding RNAs as Blood-Based Biomarkers of Diabetic Retinopathy.Translational vision science & technology · 2026
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  11. Non-coding RNA research · 2024
    Review
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  15. Potential Diagnostic Markers of Diabetic Retinopathy: Serum LncRNA MIAT, HOTTIP, SNHG16.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  16. Role of LncRNA MIAT in Diabetic Complications.Current medicinal chemistry · 2024
    Review
  17. ANRIL: A Long Noncoding RNA in Age-related Diseases.Mini reviews in medicinal chemistry · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saumik BiswasDepartment of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
Ali CoyleSchool of Biomedical Engineering, Western University, London, ON, Canada.
Shali ChenDepartment of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
Miso GostimirDepartment of Ophthalmology, Western University, London, ON, Canada.
John GonderDepartment of Ophthalmology, Western University, London, ON, Canada.
Subrata ChakrabartiDepartment of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With increasing incidence of diabetes worldwide, there is an ever-expanding number of patients with chronic diabetic complications such as diabetic retinopathy (DR), one of the leading causes of blindness in the working age population. Early screening for the onset and severity of DR is essential for timely intervention. With recent advancements in genomic technologies, epigenetic alterations in DR are beginning to unravel. Long non-coding RNAs (lncRNAs), which are key epigenetic mediators, have demonstrated implications in several (DR) related processes. Based on the previous research, we have developed a serum-based, multi-panel PCR test using 9 lncRNAs (

Indexed as

Diabetes MellitusDiabetic RetinopathyRNA, Long NoncodingEndothelial CellsGlucoseHumansRetinaGlucoseRNA, Long Noncodingbiomarkerdiabetic retinopathydiagnosisepigeneticslncRNA

Identifiers

PMID35464068
PMCPMC9022211
OpenAlexW4225656021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.