Evidence map›Paper›PMID 35463973›Full record

ArticleBioMed research international2022

Effects of Treadmill Exercise on Mitochondrial DNA Damage and Cardiomyocyte Telomerase Activity in Aging Model Rats Based on Classical Apoptosis Signaling Pathway.

Chao Liang, Xiaoli Zhou, Meiling Li, Zhengpeng Song, Jinyan Lan

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Role of telomerase in the onset and treatment of gastric cancer.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chao LiangSchool of Martial Arts, Wuhan Sports University, Wuhan 430079, China.ORCID https://orcid.org/0000-0002-2213-5681
Xiaoli ZhouShanxi Traditional Chinese Medical Hospital, Taiyuan 030012, China.
Meiling LiCollege of Physical Education, Shanxi University, Taiyuan 237016, China.
Zhengpeng SongSchool of Martial Arts, Wuhan Sports University, Wuhan 430079, China.
Jinyan LanSchool of Martial Arts, Wuhan Sports University, Wuhan 430079, China.
Wuhan Sports University · CNShanxi Province Hospital of Traditional Chinese Medicine · CNShanxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to explore the effect of treadmill exercise on mitochondrial DNA damage and myocardial telomerase activity in aging model rats based on the classical apoptosis signaling pathway, a total of 36 clean-grade male SD rats are selected. After modeling, the rats are randomly divided into groups, namely, control and 3 times/w and 6 times/w exercise rats, with 12 rats in each group. After the rats of each group are modeled, the myocardial tissue and cells are collected, the apoptosis of myocardial cells is detected by TUNEL method, and the protein expressions of Bax and Bcl-2 in myocardial tissue are detected by western blotting. The mtDNA content of the control rats is the highest, which is significantly higher than that of the exercise group (

Indexed as

AgingDNA, MitochondrialExercise TherapyMyocytes, CardiacTelomeraseAnimalsApoptosisbcl-2-Associated X ProteinMaleProto-Oncogene Proteins c-bcl-2RatsRats, Sprague-DawleySignal Transductionbcl-2-Associated X ProteinDNA, MitochondrialProto-Oncogene Proteins c-bcl-2Telomerase

Identifiers

PMID35463973
PMCPMC9023140
OpenAlexW4224014263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.