ArticleJournal of clinical pathology1987
New marker of B lymphocytes, MB2: comparison with other lymphocyte subset markers active in conventionally processed tissue sections.
Article in Journal of clinical pathology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 62 citations in OpenAlex.
- CD19 and immunophenotype of bone marrow plasma cells in monoclonal gammopathy of undetermined significance.Journal of clinical pathology · 1995Article
- CD43 expression in B cell lymphoma.Journal of clinical pathology · 1992Article
- Childhood lymphoma in Yorkshire.Journal of clinical pathology · 1992Article
- Twelve cases of Ki-1 positive anaplastic large cell lymphoma of skin.Journal of clinical pathology · 1991Article
- The immunopathology of Schistosoma mansoni granulomas in human colonic schistosomiasis.Virchows Archiv. A, Pathological anatomy and histopathology · 1990Article
- Detection of T cells in paraffin wax embedded tissue using antibodies against a peptide sequence from the CD3 antigen.Journal of clinical pathology · 1989Article
- Molecule detected in formalin fixed tissue by antibodies MT1, DF-T1, and L60 (Leu-22) corresponds to CD43 antigen.Journal of clinical pathology · 1989Article
- Primary lymphoma of the liver showing immunohistochemical evidence of T-cell origin. Successful management by right trisegmentectomy.Digestive diseases and sciences · 1988Article
- Antisera against epitopes resistant to denaturation on T3 (CD3) antigen can detect reactive and neoplastic T cells in paraffin embedded tissue biopsy specimens.Journal of clinical pathology · 1988Article
- Utilization of monoclonal antibody L26 in the identification and confirmation of B-cell lymphomas. A sensitive and specific marker applicable to formalin-and B5-fixed, paraffin-embedded tissues.The American journal of pathology · 1987Article
- Monoclonal antibody L26: an antibody that is reactive with normal and neoplastic B lymphocytes in routinely fixed and paraffin wax embedded tissues.Journal of clinical pathology · 1987Article
- The role of immunocytochemistry in diagnostic pathology.Journal of clinical pathology · 1987Review
- Demonstration of lymphoid antigens in decalcified bone marrow trephines.Journal of clinical pathology · 1987Article
- Detailed phenotypic analysis of B-cell lymphoma using a panel of antibodies reactive in routinely fixed wax-embedded tissue.The American journal of pathology · 1987Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of the murine monoclonal antibody MB2 for identifying B lymphocytes in routinely processed tissue was evaluated and contrasted with the use of the monoclonal antibody UCHL1 for identifying T cells. One hundred and sixty eight surgical biopsy specimens were immunostained with these antibodies, including a wide range of normal and neoplastic non-lymphoid tissues, as well as normal lymphoreticular tissues and lymphomas. Sixty four non-Hodgkin's lymphomas were also examined, of which 51 had been previously phenotypically defined. In selected cases the results were compared with those obtained using two other monoclonal antibodies MB1 and MT1, used for identifying B and T cells, respectively, in paraffin sections. MB1 stained a smaller proportion of B cell tumours than MB2 and staining was, in general, weaker, except in one case of centroblastic lymphoma. MT1 immunoreactivity was comparable with that of UCHL1, except in one case of T lymphoblastic lymphoma (MT1 positive, UCHL1 negative). None of the antibodies is ideal, but, if used as a panel, they permit the separation of B cells and T cells in paraffin sections.
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