Evidence map›Paper›PMID 35463877›Full record

ArticleFrontiers in pediatrics2022

Newborn Weight Loss as a Predictor of Persistence of Exclusive Breastfeeding up to 6 Months.

Enrica Delfino, Luca Peano, Roberto Giorgio Wetzl, Maria Lorella Giannì, Roberta Netto, Alessandra Consales, Maria Enrica Bettinelli, Daniela Morniroli, Francesca Vielmi, Fabio Mosca and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07320287 (A Randomized, Blinded, Controlled Trial to Evaluate Effects of Multi-strain Bacillus Spore Probiotic Supplements), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07320287 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Randomized, Blinded, Controlled Trial to Evaluate Effects of Multi-strain Bacillus Spore Probiotic Supplements (LiveSpo PREG-MOM and LiveSpo CONSY) on Growth Metrics, Prevention of Functional Gastrointestinal Disorders, and Modulation of the Gut Microbiota in Cesarean-Delivered Neonates

TypeinterventionalSponsorAnabio R&DRan2026 to 2027Enrolled180ConditionsFunctional Gastrointestinal Disorders (FGIDs), Weight LossArmsRO water, LiveSpo PREG-MOM, LiveSpo CONSY
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Enrica DelfinoDepartment of Anesthesia, Intensive Care, and Out-Hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Luca PeanoDepartment of Pediatrics, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Roberto Giorgio WetzlDepartment of Anesthesia, Intensive Care, and Out-Hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Maria Lorella GiannìDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Roberta NettoDepartment of Anesthesia, Intensive Care, and Out-Hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Alessandra ConsalesDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Maria Enrica BettinelliDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Daniela MorniroliDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Francesca VielmiDepartment of Pediatrics, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Fabio MoscaDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Luca MontagnaniDepartment of Anesthesia, Intensive Care, and Out-Hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Italy.
Azienda USL della Valle d’Aosta · ITUniversity of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the association between neonatal weight loss and persistence of exclusive breastfeeding up to 6 months. Study Design: An observational cohort study in the setting of a Baby Friendly Hospital, enrolling 1,260 healthy term dyads. Neonatal percentage of weight loss was collected between 48 and 72 h from birth. Using a questionnaire, all mothers were asked on the phone what the infant's mode of feeding at 10 days, 42 days and 6 months (≥183 days) from birth were. The persistence of exclusive breastfeeding up to 6 months and the occurrence of each event that led to the interruption of exclusive breastfeeding were verified through a logistic analysis that included 40 confounders. Results: Infants with a weight loss ≥7% were exclusively breastfed at 6 months in a significantly lower percentage of cases than infants with a weight loss <7% (95% CI 0.563 to 0.734, Conclusions: With the limitations of a single-center study, a weight loss ≥7% in the first 72 h after birth appears to be a predictor of an early interruption of exclusive breastfeeding before the recommended 6 months in healthy term exclusively breastfed newborns.

Indexed as

complementary feedingexclusive breastfeeding up to 6 monthsexclusive formula feedingintegration with formulanewborn weight lossweaningweight loss higher than 7%weight loss up to 7%

Identifiers

PMID35463877
PMCPMC9021796
OpenAlexW4225547342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.