Evidence map›Paper›PMID 35463842›Full record

ArticleJournal of chiropractic medicine2021

Secretory Immunoglobulin A and Upper Cervical Chiropractic: A Preliminary Prospective, Multicenter, Observational Study.

Philip R Schalow, Kelly A Kimball, Frederick T Schurger, George R Sooley, Scott P Bales, Roderic P Rochester, Robert T Brooks, Julie M Hunt

Abstract read
In one paragraph

Article in Journal of chiropractic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philip R SchalowPrivate practice, Rockford, Illinois.
Kelly A KimballInternational Chiropractors Association, Falls Church, Virginia.
Frederick T SchurgerPrivate practice, Springfield, Illinois.
George R SooleyPrivate practice, Danville, Illinois.
Scott P BalesPrivate practice, Alliston, Ontario, Canada.
Roderic P RochesterPrivate practice, Clarkesville, Georgia.
Robert T BrooksTulsa, Oklahoma.
Julie M HuntPrivate practice, Clearwater, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to observe changes in secretory immunoglobulin A (SIgA) after chiropractic care using upper cervical adjusting techniques (UCATs) at the craniocervical junction (CCJ). Methods: Forty-one participants were enrolled from 5 chiropractic offices in North America. Each participant provided a saliva sample at an initial visit before care. A second saliva sample was collected after resting 30 minutes after the first UCAT treatment. A third saliva sample was collected after 2 weeks. Results: There was a significant increase in SIgA observed 30 minutes after the UCAT treatment compared to baseline. After 2 weeks, SIgA levels decreased back to near original levels. Conclusion: Our preliminary findings demonstrate an immediate, temporary increase in SIgA levels after a UCAT treatment at the CCJ.

Indexed as

ChiropracticImmunity, MucosalImmunoglobulin A, Secretory

Identifiers

PMID35463842
PMCPMC9023133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.