Evidence map›Paper›PMID 35463780›Full record

SynthesisFrontiers in cardiovascular medicine2022

Prognostic Outcome of New-Onset Left Bundle Branch Block After Transcatheter Aortic Valve Replacement in Patients With Aortic Stenosis: A Systematic Review and Meta-Analysis.

Jialu Wang, Shidong Liu, Xiangxiang Han, Yang Chen, Hao Chen, Zunhui Wan, Bing Song

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Conduction Disorders: The Achilles' Heel of TAVR?Journal of clinical medicine · 2026
    Review
  4. Article
  5. Article
  6. Late arrhythmic burden in patients with left bundle branch block after TAVR with the Evolut valve.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jialu WangThe First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China.
Shidong LiuDepartment of Cardiovascular Surgery, First Hospital of Lanzhou University, Lanzhou, China.
Xiangxiang HanThe First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China.
Yang ChenThe First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China.
Hao ChenThe First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China.
Zunhui WanDepartment of Cardiovascular Surgery, First Hospital of Lanzhou University, Lanzhou, China.
Bing SongDepartment of Cardiovascular Surgery, First Hospital of Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left bundle branch block (LBBB) is a common complication of the transcatheter aortic valve replacement (TAVR), and its impact on prognosis is controversial. Methods: A comprehensive electronic search was conducted in databases (PubMed, Embase, Cochrane Library, and The Web of Science), from the date of database establishment till March 2021, to screen for studies on new-onset LBBB after TAVR. We next performed a meta-analysis to evaluate the effect of new-onset LBBB after TAVR on patient prognosis, based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results: A total of 17 studies, including 9205 patients, were eligible for our analysis. Patients with new-onset LBBB had elevated all-cause mortality risk verses patients without new-onset LBBB, during all follow ups. The relevant data are as follows: 30-day (RR:1.71; 95%CI:1.27-2.29; Conclusion: Patients with new-onset LBBB have worse prognosis after TAVR than those without new-onset LBBB. Recognition of the adverse effects of post-TAVR new-onset LBBB can lead to the development of new strategies that enhance clinical outcomes. Systematic Trial Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=197224, identifier: 19722.

Indexed as

hospitalization for heart failureleft bundle branch blockmortalitypermanent pacemaker implantationtranscatheter aortic valve replacement

Identifiers

PMID35463780
PMCPMC9024042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.