Evidence map›Paper›PMID 35463692›Full record

ArticleJournal of healthcare engineering2022

Pramipexole Inhibits Neuronal Apoptosis in Rats with Parkinson's Disease.

Yongqi Sun, Baohong Cui, Lin Ye, Yunxin Hu, Yujun Pan

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yongqi SunDepartment of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China.
Baohong CuiLaboratory Medicine, The Third Affiliated Hospital of Harbin Medical University, Harbin, China.
Lin YeDepartment of Rehabilitation, Xuanwu Hospital Affiliated to Capital Medical University, Beijing, China.
Yunxin HuDepartment of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China.
Yujun PanDepartment of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID 0000-0002-8610-1755
Guangdong 999 Brain Hospital · CNHarbin Medical University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the inhibition of pramipexole on the neuronal apoptosis and its influences on the expressions of brain tissue brain-derived neurotrophic factor (BDNF), and serum miR-103a and miR-30b and inflammatory factors in rats with Parkinson's disease. A total of 36 Sprague-Dawley rats were randomly divided into normal group (

Indexed as

MicroRNAsParkinson DiseaseAnimalsApoptosisbcl-2-Associated X ProteinBrain-Derived Neurotrophic FactorPramipexoleProto-Oncogene Proteins c-bcl-2RatsRats, Sprague-Dawleybcl-2-Associated X ProteinBrain-Derived Neurotrophic FactorMicroRNAsPramipexoleProto-Oncogene Proteins c-bcl-2

Identifiers

PMID35463692
PMCPMC9020956
OpenAlexW4224035778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.