Evidence map›Paper›PMID 35463668›Full record

ArticleJournal of healthcare engineering2022

Reduced Incidence of Necrotizing Enterocolitis due to the Anti-Inflammatory Effects of CXCL14 in Intestinal Tissue.

Xu Sun, Lingqi Xu, Shurong Ma, Lulu Chen, Ruze Tang, Dashuang Li, Fangjie Hu, Ting Wang, Yuan Gong, Huiting Zhou and 1 more

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xu SunInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.ORCID 0000-0002-8200-654X
Lingqi XuInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Shurong MaInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Lulu ChenInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Ruze TangInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Dashuang LiInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Fangjie HuInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Ting WangInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Yuan GongInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Huiting ZhouInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.
Jian WangInstitute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China.ORCID 0000-0001-9612-5382
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioinformatic analysis indicated that downregulated CXCL14 will occur in the intestinal tissue of patients with necrotizing enterocolitis (NEC). To reveal the relationship between CXCL14 and mucosal immune regulation, we designed and implemented the experiments to explore the potential function of CXCL14 in the pathogenesis of NEC. Firstly, this study confirmed that the expression of CXCL14 decreased in the intestinal tract of NEC children. Secondly, the experiments results showed that CXCL14 could ameliorate the inflammatory injury of intestinal tissue through the suppressive effect on the expression of TNF-

Indexed as

Enterocolitis, NecrotizingAnimalsAnti-Inflammatory AgentsChemokines, CXCHumansIncidenceInfant, NewbornMiceTumor Necrosis Factor-alphaAnti-Inflammatory AgentsChemokines, CXCCXCL14 protein, humanCXCL14 protein, mouseTumor Necrosis Factor-alpha

Identifiers

PMID35463668
PMCPMC9023168
OpenAlexW4224295031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.