Evidence map›Paper›PMID 35463638›Full record

ArticleFrontiers in cellular and infection microbiology2022

Anti-Gametocyte Antigen Humoral Immunity and Gametocytemia During Treatment of Uncomplicated Falciparum Malaria: A Multi-National Study.

Katherine O'Flaherty, Jo-Anne Chan, Julia C Cutts, Sophie G Zaloumis, Elizabeth A Ashley, Aung Pyae Phyo, Damien R Drew, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda and 19 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 15 institutions in 12 countries.

Katherine O'FlahertyLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Jo-Anne ChanLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Julia C CuttsLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Sophie G ZaloumisCentre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.
Elizabeth A AshleyMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Aung Pyae PhyoMyanmar Oxford Clinical Research Unit, Yangon, Myanmar.
Damien R DrewLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Arjen M DondorpMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Nicholas P DayMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Mehul DhordaMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Rick M FairhurstLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Pharath LimLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Chanaki AmaratungaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Sasithon PukrittayakameeFaculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Tran Tinh HienMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Ye HtutDepartment of Medical Research, Ministry of Health and Sports, Yangon, Myanmar.
Mayfong MayxayCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
M Abul FaizMalaria Research Group and Dev Care Foundation, Chittagong, Bangladesh.
Olugbenga A MokuoluDepartment of Paediatrics and Child Health, University of Ilorin, Ilorin, Nigeria.
Marie A OnyambokoKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Caterina FanelloMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Eizo TakashimaDivision of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Japan.
Takafumi TsuboiDivision of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Japan.
Michael TheisenDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Francois NostenMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
James G BeesonLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Julie A SimpsonCentre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.
Nicholas J WhiteMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Freya J I FowkesLife Sciences, Burnet Institute, Melbourne, VIC, Australia.
Burnet Institute · AUMahidol Oxford Tropical Medicine Research Unit · THMahidol University · THUniversity of Melbourne · AUUniversity of Oxford · GBEhime University · JPNational Institute of Allergy and Infectious Diseases · USChild Health Research Foundation · BDMahosot Hospital · LAMinistry of Health and Sports · MMMyanmar Oxford Clinical Research Unit · MMNational Institutes of Health · USUniversity of Copenhagen · DKUniversity of Ilorin · NGUniversity of Kinshasa · CD

Funding

Wellcome Trust
6 · The paper itself

Abstract

Introduction: Understanding the human immune response to Methods: In a multi-national clinical efficacy trial of artemisinin therapies (13 sites of varying transmission over South-East Asia and Africa), we measured Immunoglobulin G (IgG) responses to recombinant Results: Microscopy detectable gametocytemia was observed in 11% (127/1,114) of participants at enrolment, and an additional 9% (95/1,114) over the follow-up period (up to day 42) (total 20% of participants [222/1,114]). IgG levels in response to Conclusion:

Indexed as

MalariaMalaria, FalciparumAntibodies, ProtozoanAntigens, ProtozoanHumansImmunity, HumoralImmunoglobulin GPlasmodium falciparumSeroepidemiologic StudiesAntibodies, ProtozoanAntigens, ProtozoanImmunoglobulin Gantibodiesclinical malariaepidemiogyfalciparum malariagametocyteimmunitymalaria

Identifiers

PMID35463638
PMCPMC9022117
OpenAlexW4226291692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.