Evidence map›Paper›PMID 35463549›Full record

ReviewMedical journal, Armed Forces India2022

Drug update - Baloxavir marboxil: Latest entrant into the arena of pharmacotherapy of influenza.

A Tejus, A G Mathur, Sapna Pradhan, Salma Malik, Md Fadil Salmani

Open access · greenAbstract readReview
In one paragraph

Review in Medical journal, Armed Forces India, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A TejusClassified Specialist (Pharmacology), Medical Officer, HQ IMTRAT, C/o 99 APO, India.
A G MathurBrig Med, 1 Corps, India.
Sapna PradhanProfessor (Pharmacology), Army College of Medical Sciences, Delhi Cantt, India.
Salma MalikDemonstrator (Pharmacology), Army College of Medical Sciences, Delhi Cantt, India.
Md Fadil SalmaniDemonstrator (Pharmacology), Army College of Medical Sciences, Delhi Cantt, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza is a frequent cause of clinically significant human disease, with seasonal epidemics and occasional pandemics. Uncomplicated influenza in healthy individuals is managed symptomatically. Vaccination against influenza plays a vital role in the control of infection in humans. The currently available antivirals include adamantanes, neuraminidase inhibitors, and ribavirin. Baloxavir marboxil, the prodrug of baloxavir, is the latest addition to the family of anti-influenza drugs, and it received US-FDA approval on October 24, 2018. Baloxavir acts through a novel mechanism of inhibiting Cap-dependent endonuclease (CEN), the vital step in the transcription of viral RNA, and prevents further spread of the virus.

Indexed as

Baloxavir marboxilCap dependent endonucleaseInfluenza

Identifiers

PMID35463549
PMCPMC9023778
OpenAlexW3214952870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.