Evidence map›Paper›PMID 35463482›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2022

Treatment of COVID-19 Acute Respiratory Distress Syndrome With a Tabletop Noninvasive Ventilation Device in a Respiratory Intermediate Care Unit.

Barney Thomas Jesudason Isaac, Nadesan Priya, Avinash Anil Nair, Balamugesh Thangakunam, Amith Balachandran, Tina George, Sheba Meriam Thomas, Tarun Kottukulam George, Ramya Iyadurai, Selwyn Selva Kumar and 9 more

Open access · goldAbstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 2 countries.

Barney Thomas Jesudason IsaacDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Nadesan PriyaDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Avinash Anil NairDepartment of Respiratory Medicine, Christian Medical College, Vellore, India.
Balamugesh ThangakunamDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Amith BalachandranDepartment of General Medicine, Christian Medical College, Vellore, India.
Tina GeorgeDepartment of General Medicine, Christian Medical College, Vellore, India.
Sheba Meriam ThomasDepartment of General Medicine, Christian Medical College, Vellore, India.
Tarun Kottukulam GeorgeDepartment of General Medicine, Christian Medical College, Vellore, India.
Ramya IyaduraiDepartment of General Medicine, Christian Medical College, Vellore, India.
Selwyn Selva KumarDepartment of Infectious Diseases, Christian Medical College, Vellore, India.
Anand ZachariahDepartment of General Medicine, Christian Medical College, Vellore, India.
Bhagteshwar SinghDepartment of Infectious Diseases, Christian Medical College, Vellore, India.
Priscilla RupaliDepartment of Infectious Diseases, Christian Medical College, Vellore, India.
Kishore PichamuthuDepartment of Medical ICU, Christian Medical College, Vellore, India.
Richa GuptaDepartment of Respiratory Medicine, Christian Medical College, Vellore, India.
Jefferson DanielDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Jebin Roger SasikumarDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Sujith Thomas ChandyDepartment of Respiratory Medicine, Christian Medical College, Vellore, India.
Devasahayam Jesudas ChristopherDepartment of Pulmonary Medicine, Christian Medical College, Vellore, India.
Christian Medical College & Hospital · INRoyal Liverpool University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the outcomes of noninvasive ventilation (NIV) administered through a tabletop device for coronavirus disease 2019 acute respiratory distress syndrome in the respiratory intermediate care unit (RIMCU) at a tertiary care hospital in India. Patients and Methods: We retrospectively studied a cohort of hospitalized patients deteriorating despite low-flow oxygen support who received protocolized management with positive airway pressure using a tabletop NIV device in the RIMCU as a step-up rescue therapy from July 30, 2020 to November 14, 2020. Treatment was commenced on the continuous positive airway pressure mode up to a pressure of 10 cm of H Results: In total, 246 patients were treated in the RIMCU during the study period. Of these, 168 received respiratory support via a tabletop NIV device as a step-up rescue therapy. Their mean age was 54 years, and 83% were men. Diabetes mellitus (78%) and hypertension (44%) were the commonest comorbidities. Treatment was successful with tabletop NIV in 77% (129/168) of the patients; of them, 41% (69/168) received treatment with continuous positive airway pressure alone and 36% (60/168) received additional increased inspiratory pressure via the bilevel positive air pressure mode. Conclusion: Respiratory support using the tabletop NIV device was an effective and economical treatment for coronavirus disease 2019 acute respiratory distress syndrome. Further studies are required to assess the appropriate time of initiation for maximal benefits and judicious utilization of resources.

Indexed as

ARDS, acute respiratory distress syndromeBPAP, bilevel positive airway pressureCARDS, coronavirus disease 2019 acute respiratory distress syndromeCOVID-19, coronavirus disease 19CPAP, continuous positive airway pressureHFNO, high-flow nasal oxygenICU, intensive care unitIMV, invasive mechanical ventilationIPAP, inspiratory positive airway pressureNIV, noninvasive ventilationPEEP, positive end-expiratory pressureRIMCU, respiratory intermediate care unit

Identifiers

PMID35463482
PMCPMC9015959
OpenAlexW4224286916

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.