Evidence map›Paper›PMID 35463152›Full record

ArticleFrontiers in neurology2022

Idiopathic Aqueductal Stenosis: Late Neurocognitive Outcome in ETV Operated Adult Patients.

Matteo Martinoni, Giovanni Miccoli, Luca Albini Riccioli, Francesca Santoro, Giacomo Bertolini, Corrado Zenesini, Diego Mazzatenta, Alfredo Conti, Luigi Maria Cavallo, Giorgio Palandri

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Matteo MartinoniIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Giovanni MiccoliDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Luca Albini RiccioliNeuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Francesca SantoroNeurology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Giacomo BertoliniIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Corrado ZenesiniEpidemiology and Biostatistics Service, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Diego MazzatentaIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Alfredo ContiIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Luigi Maria CavalloDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Giorgio PalandriIRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Istituto delle Scienze Neurologiche di Bologna · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of the present study is to evaluate a neurocognitive outcome in patients affected by late-onset idiopathic aqueductal stenosis (LIAS) who underwent endoscopic third ventriculostomy (ETV). Materials and Methods: A prospective study was conducted between January 2015 and December 2017 in a series of 10 consecutive adult patients referred to the Neurosurgery Department of IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy. All the adult patients admitted with absence of CSF flow through the aqueduct in phase-contrast (PC)-MRI sequences or a turbulence void signal in T2-weighted images in midsagittal thin-slice MR sequences underwent a specific neuroradiological, neurological, and neurocognitive assessment pre- and postoperatively. Results: All patients affected by gait and sphincter disturbances improved after ETV. Attentive and executive functions as well as visuo-spatial memory and verbal executive functions improved in several patients. Similarly, the affective and behavioral scales improved in almost 50% of the patients. No major complications have been recorded, and no patients required a second surgery for shunt placement. Conclusion: Endoscopic third ventriculostomy represents a safe and effective surgical procedure for the treatment of LIAS. In addition to neurological improvement, we demonstrated also postoperative neurocognitive improvement mainly in attentive and executive functions, visuo-spatial memory, verbal executive functions, and behavioral and affective domains.

Indexed as

aqueductal stenosischronic adult hydrocephalusendoscopic third ventriculostomyhydrocephaluslate onset hydrocephalusLIAS

Identifiers

PMID35463152
PMCPMC9021920
OpenAlexW4226075512

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.