ArticleFrontiers in neurology2022
Early Edema Within the Ischemic Core Is Time-Dependent and Associated With Functional Outcomes of Acute Ischemic Stroke Patients.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Net water uptake as a predictive neuroimaging marker for acute ischemic stroke outcomes: a meta-analysis.European radiology · 2024Pooled it
- Dual-energy computed tomography angiography-based quantification of lesion net water uptake to identify stroke onset time.Heliyon · 2024Article
- Protein nanoparticles induce the activation of voltage-dependent non-selective ion channels to modulate biological osmotic pressure in cytotoxic cerebral edema.Frontiers in pharmacology · 2024Article
- ASPECTS-based net water uptake outperforms target mismatch for outcome prediction in patients with acute ischemic stroke and late therapeutic window.European radiology · 2023Article
- Net water uptake within the ischemic penumbra predicts the presence of the midline shift in patients with acute ischemic stroke.Frontiers in neurology · 2023Article
- Net water uptake and ASPECTS in predicting futile recanalization for acute large vessel occlusion stroke: insights from time window stratification.Frontiers in neurologyArticle
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Authors and funding
9 authors.
Funding
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Abstract
Objective: To investigate the difference in early edema, quantified by net water uptake (NWU) based on computed tomography (CT) between ischemic core and penumbra and to explore predictors of NWU and test its predictive power for clinical outcome. Methods: Retrospective analysis was conducted on patients admitted to Ningbo First Hospital with anterior circulation stroke and multi-modal CT. In 154 included patients, NWU of the ischemic core and penumbra were calculated and compared by Mann-Whitney Results: The NWU within the ischemic core [6.1% (2.9-9.2%)] was significantly higher than that of the penumbra [1.8% (-0.8-4.0%)]. The only significant predictor of NWU within the ischemic core was infarct time ( Conclusions: Early edema quantified by NWU is relatively limited in the ischemic core and develops in a time-dependent manner. NWU estimates within the ischemic core may help to predict clinical outcomes of patients with acute ischemic stroke.
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