Evidence map›Paper›PMID 35463127›Full record

ReviewFrontiers in neurology2022

Remote Memory in Epilepsy: Assessment, Impairment, and Implications Regarding Hippocampal Function.

Sanya Rastogi, Kimford J Meador, William B Barr, Orrin Devinsky, Beth A Leeman-Markowski

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sanya RastogiEpilepsy and Cognition Laboratory, Veterans Affairs, New York Harbor Healthcare System, Research Service, New York, NY, United States.
Kimford J MeadorDepartment of Neurology and Neurological Sciences, Comprehensive Epilepsy Program, Stanford University School of Medicine, Palo Alto, CA, United States.
William B BarrDepartment of Neurology, Comprehensive Epilepsy Center, New York University Langone Health, New York, NY, United States.
Orrin DevinskyDepartment of Neurology, Comprehensive Epilepsy Center, New York University Langone Health, New York, NY, United States.
Beth A Leeman-MarkowskiEpilepsy and Cognition Laboratory, Veterans Affairs, New York Harbor Healthcare System, Research Service, New York, NY, United States.

Funding

CSRD VA IK2 CX001255
6 · The paper itself

Abstract

Studies of epilepsy patients provide insight into the neuroscience of human memory. Patients with remote memory deficits may learn new information but have difficulty recalling events from years past. The processes underlying remote memory impairment are unclear and likely result from the interaction of multiple factors, including hippocampal dysfunction. The hippocampus likely has a continued role in remote semantic and episodic memory storage over time, and patients with mesial temporal lobe epilepsy (TLE) are at particular risk for deficits. Studies have focused on lateralization of remote memory, often with greater impairment in left TLE, which may relate to verbal task demands. Remote memory testing is restricted by methodological limitations. As a result, deficits have been difficult to measure. This review of remote memory focuses on evidence for its underlying neurobiology, theoretical implications for hippocampal function, and methodological difficulties that complicate testing in epilepsy patients.

Indexed as

autobiographical memoryconsolidationepilepsyepisodic memoryhippocampuslong-term memoryremote memoryseizures

Identifiers

PMID35463127
PMCPMC9024073

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.