Evidence map›Paper›PMID 35463105›Full record

ArticleIndian journal of clinical biochemistry : IJCB2022

A Study of the Levels of Some Toxic Substances present in Dry Holi Colours in Kolkata, India.

Krishnajyoti Goswami, Ipsita Mazumdar

Open access · greenAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Krishnajyoti GoswamiFaculty of Medicine, Lincoln University College, Kuala Lumpur, Malaysia.ORCID 0000-0003-4383-7284
Ipsita MazumdarDepartment of Biochemistry, KPC Medical College, Kolkata, India.
KPC Medical College and Hospital · INLincoln University College · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

'Holi' is an Indian festival with a great cultural context, that is celebrated across the world at the onset of spring by applying dry powder of vibrant colours on friends and family. In ancient times holi colours were prepared from different spring flowers, but in modern times, these natural colours have been replaced by commercial industrial dyes prepared by chemical processes. Even products that claim to use organic colours, use synthetic pigments to enhance the brightness of hues. Such synthetic holi colours are sold as herbal colours, in an unregulated manner, in local markets, and no checks can be enforced on the product composition. Also, the quality and the amount of information about the ingredients of the particular packets are missing. These colours sold in the local market often contain hazardous chemicals such as endotoxins, and heavy metals, like lead, potentially causing moderate to severe health problem. Holi colour samples were randomly collected from different sites in Kolkata, India. Red, pink, violet, green and yellow coloured powders were obtained. The powders were prepared and analysed for lead content by Inductively Coupled Plasma-Mass Spectrometric method. Analysis of endotoxin content of different holi colours was also performed by Limulus Amebocyte Lysate test. The lead content was found to be almost 2 times higher in the holi colours, with yellow pigment having the highest concentration, than FDA Standard for maximum permissible limit in cosmetics, which was taken as a reference for safety limit of lead that is dermatologically applicable. The endotoxin levels are alarmingly high, with almost 35 times the FDA reference for dermatological safety limit. Special attention should be given to lead and endotoxin levels in holi colours as their consequences pose serious health threats. Therefore, quality control measures should be recommended for them, in par with products designed for long-term contact with the skin.

Indexed as

EndotoxinHoli ColourLAL TestLeadMass Spectroscopy

Identifiers

PMID35463105
PMCPMC8994014
OpenAlexW3154501554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.