Evidence map›Paper›PMID 35463064›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Electroacupuncture Attenuates Learning and Memory Impairment via PI3K/Akt Pathway in an Amyloid

Si-Mai Shao, Kyung Hye Park, Ye Yuan, Zijuan Zhang, Yanwen You, Zhenqiang Zhang, Li Hao

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Mechanisms of comorbidity between Alzheimer's disease and pain.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Si-Mai ShaoMedical College, Henan University of Chinese Medicine, Zhengzhou, China.ORCID https://orcid.org/0000-0001-8267-6570
Kyung Hye ParkAcademy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, China.
Ye YuanAcademy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, China.
Zijuan ZhangMedical College, Henan University of Chinese Medicine, Zhengzhou, China.
Yanwen YouMedical College, Henan University of Chinese Medicine, Zhengzhou, China.
Zhenqiang ZhangAcademy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, China.ORCID https://orcid.org/0000-0001-9774-4054
Li HaoMedical College, Henan University of Chinese Medicine, Zhengzhou, China.ORCID https://orcid.org/0000-0002-9569-0125
First Affiliated Hospital of Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main characteristic of Alzheimer's disease (AD) is the progressive decline of learning and memory ability. Electroacupuncture (EA) may improve AD-related learning and memory ability. However, the underlying molecular mechanism of action remains unclear. The objective of the present study was to assess the effects and the molecular mechanism of EA on learning and memory in an amyloid

Identifiers

PMID35463064
PMCPMC9033336
OpenAlexW4223972772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.