ArticleFrontiers in medicine2022
Association Between Platelet Levels and 28-Day Mortality in Patients With Sepsis: A Retrospective Analysis of a Large Clinical Database MIMIC-IV.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 34 citations in OpenAlex.
- Association between platelet count and 30-day mortality in community-acquired pneumonia patients receiving systemic glucocorticoids therapy.Scientific reports · 2026Article
- Platelet hypoaggregation in septic shock: temporal dynamics and association with multiorgan failure-a propensity score-matched cohort study.BMC anesthesiology · 2026Article
- Determinants of fatal outcome in septic shock patients with euthyroid sick syndrome.World journal of critical care medicine · 2026Article
- Predictive Value of Platelet-Based Indexes for Mortality in Sepsis.Biomedicines · 2026Article
- The Impact of Age on In-Hospital Mortality in Patients with Sepsis: Findings from a Nationwide Study.Journal of clinical medicine · 2025Article
- The impact of thrombocytopenia on mortality in infective endocarditis - aInternational journal of cardiology. Heart & vasculature · 2025Review
- Time series analysis between platelet counts and 60-day mortality in sepsis patients with thrombocytopenia: a retrospective cohort study.BMC infectious diseases · 2025Observational
- Association between endothelial activation and stress index and all-cause mortality risk in sepsis patients: a retrospective cohort analysis utilizing the MIMIC-IV database.BMC infectious diseases · 2025Article
- Early dynamic changes in platelet counts and 28-day mortality in sepsis patients: a retrospective cohort study using dynamic latent class model and generalized additive mixture model analysis.Frontiers in medicine · 2025Article
- Development and validation of a machine learning model for in-hospital mortality prediction in children under 5 years with heart failure.Frontiers in pediatrics · 2025Article
- Advanced biomarker clustering analysis reveals mortality predictors in burn patients with sepsis.Scientific reports · 2024Article
- Platelet count as a prognostic marker for acute respiratory distress syndrome.BMC pulmonary medicine · 2024Article
- The prognostic value of postoperative platelet levels in elderly patients after valve replacement surgery: a retrospective cohort study.BMC cardiovascular disorders · 2024Article
- Associations between static and dynamic changes of platelet counts and in-hospital mortality in critical patients with acute heart failure.Scientific reports · 2024Article
- Association of a decreased platelet count with poor survival in patients with adult secondary hemophagocytic lymphohistiocytosis.Annals of hematology · 2024Article
- Non-linear relationship between platelet count and 28-day mortality in critically ill patients with infective endocarditis: a retrospective cohort study from MIMIC IV database.Frontiers in cardiovascular medicine · 2024Article
- Association between platelet count and 30-day in-hospital mortality among intensive care unit patients with sepsis: a multicenter retrospective cohort study.Frontiers in medicine · 2024Article
- The correlation of hemoglobin and 28-day mortality in septic patients: secondary data mining using the MIMIC-IV database.BMC infectious diseases · 2023Article
- Predicting in-hospital mortality in pulmonary embolism patients: development and external validation of the PATHOS score.Clinical and experimental emergency medicine · 2023Article
- Association Between Endothelial Activation and Stress Index and 28-Day Mortality in Septic ICU patients: a Retrospective Cohort Study.International journal of medical sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This research focused on evaluating the correlation between platelet count and sepsis prognosis, and even the dose-response relationship, in a cohort of American adults. Method: Platelet counts were recorded retrospectively after hospitalization for patients admitted to Beth Israel Deaconess Medical Center's intensive care unit between 2008 and 2019. On admission to the intensive care unit, sepsis patients were divided into four categories based on platelet counts (very low < 50 × 10 Results: The risk of 28-day septic mortality was nearly 2-fold higher in the platelet very low group when compared to the low group (hazard ratios [HRs], 2.24; 95% confidence interval [CI], 1.92-2.6). Further analysis revealed a curvilinear association between platelets and the sepsis risk of death, with a saturation effect predicted at 100 × 10 Conclusion: When platelet count was less than 100 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.