Evidence map›Paper›PMID 35462990›Full record

ArticleFrontiers in medicine2022

Development of Alveolar Hemorrhage After Pfizer-BioNTech COVID-19 mRNA Vaccination in a Patient With Renal-Limited Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Report.

Ken Nishioka, Shintaro Yamaguchi, Itaru Yasuda, Norifumi Yoshimoto, Daiki Kojima, Kenji Kaneko, Mitsuhiro Aso, Tomoki Nagasaka, Eriko Yoshida, Kiyotaka Uchiyama and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Ken NishiokaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Shintaro YamaguchiDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Itaru YasudaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Norifumi YoshimotoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Daiki KojimaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Kenji KanekoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Mitsuhiro AsoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Tomoki NagasakaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Eriko YoshidaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Kiyotaka UchiyamaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Takaya TajimaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Jun YoshinoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Tadashi YoshidaApheresis and Dialysis Center, Keio University School of Medicine, Tokyo, Japan.
Takeshi KandaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Hiroshi ItohDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Tokyo, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the coronavirus disease 2019 (COVID-19) pandemic continues and a new variant of the virus has emerged, the COVID-19 vaccination campaign has progressed. Rare but severe adverse outcomes of COVID-19 vaccination such as anaphylaxis and myocarditis have begun to be noticed. Of note, several cases of new-onset antineutrophil cytoplasmic antibody-associated vasculitis (AAV) after COVID-19 mRNA vaccination have been reported. However, relapse of AAV in remission has not been recognized enough as an adverse outcome of COVID-19 vaccination. We report, to our knowledge, a first case of renal-limited AAV in remission using every 6-month rituximab administration that relapsed with pulmonary hemorrhage, but not glomerulonephritis, following the first dose of the Pfizer-BioNTech COVID-19 vaccine. The patient received the COVID-19 vaccine more than 6 months after the last dose of rituximab according to the recommendations. However, his CD19

Indexed as

alveolar hemorrhageCOVID-19 mRNA vaccinationrelapserenal-limited ANCA-associated vasculitisrituximab

Identifiers

PMID35462990
PMCPMC9023855
OpenAlexW4225358730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.