Evidence map›Paper›PMID 35462614›Full record

ArticleFunction (Oxford, England)2022

ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α

Ivan Kadurin, Shehrazade Dahimene, Karen M Page, Joseph I J Ellaway, Kanchan Chaggar, Linda Troeberg, Hideaki Nagase, Annette C Dolphin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Function (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ivan KadurinDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Shehrazade DahimeneDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Karen M PageDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Joseph I J EllawayDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Kanchan ChaggarDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
Linda TroebergNorwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.
Hideaki NagaseKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Annette C DolphinDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
University College London · GBUniversity of East Anglia · GBUniversity of Oxford · GB

Funding

British Heart Foundation PG/18/83/34123Medical Research Council MR/W001373/1Wellcome TrustWellcome Trust 206279/Z/17/Z
6 · The paper itself

Abstract

The auxiliary α

Indexed as

NeuralgiaTissue Inhibitor of Metalloproteinase-3ADAM17 ProteinCalcium Channels, N-TypeCalcium, DietaryHumansPeptide HydrolasesProteolysisADAM17 ProteinADAM17 protein, humanCalcium Channels, N-TypeCalcium, DietaryPeptide HydrolasesTissue Inhibitor of Metalloproteinase-3ADAM17calcium channelcalcium currentsmatrix metalloproteasetraffickingα2δ subunit

Identifiers

PMID35462614
PMCPMC9016415
OpenAlexW4220915631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.