ArticleBMC medicine2022
Time spent in outdoor light is associated with the risk of dementia: a prospective cohort study of 362094 participants.
Article in BMC medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Seeing through the veil: blue-light filtering and peak contrast sensitivity in pseudophakic patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Functional and morphological alterations of light detection circuits in postmortem retina from donors with different stages of Alzheimer's-like pathology.Communications biology · 2026Article
- Associations between wearable-device-measured daytime and nighttime light exposures and dementia risk: A prospective cohort study.General psychiatry · 2026Article
- Association between sleep, sunlight exposure, and multimorbidity in older adults with and without mental illness.Frontiers in public health · 2026Article
- Association between sunlight exposure and risk of rheumatic diseases: a prospective cohort study in the UK.Frontiers in public health · 2026Article
- Vitamin deficiencies and Alzheimer's disease: evidence and implications for supplementation.Frontiers in nutrition · 2026Review
- Photosensitivity of an aging brain.bioRxiv : the preprint server for biology · 2025Article
- Outdoor light spending time, genetic predisposition and incident Parkinson's disease: the mediating effect of lifestyle and vitamin D.Journal of health, population, and nutrition · 2025Article
- The association between time spent outdoors during daylight and mortality among participants of the Adventist Health Study 2 Cohort.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data.Health science reports · 2025Article
- Facial aging, cognitive impairment, and dementia risk.Alzheimer's research & therapy · 2024Article
- Identifying modifiable factors associated with neuroimaging markers of brain health.CNS neuroscience & therapeutics · 2024Article
- Sex-specific social, lifestyle, and physical health risk factors in cataracts development.Eye (London, England) · 2024Article
- Fish oil supplementation and risk of incident systemic lupus erythematosus: a large population-based prospective study.Nutrition journal · 2024Article
- The impact of sunlight exposure on brain structural markers in the UK Biobank.Scientific reports · 2024Article
- Self-Reported Outdoor Light Exposure Time and Incident Heart Failure.Journal of the American Heart Association · 2024Article
- Association of time spent outdoors with the risk of Parkinson's disease: a prospective cohort study of 329,359 participants.BMC neurology · 2024Article
- Reliability and validity of the Chinese version of the sunlight exposure questionnaire.Frontiers in public health · 2024Article
- Effect of Personalized Blue-Enriched White Light Intervention on Rest-Activity and Light Exposure Rhythms in Mild and Moderate Alzheimer's Disease.Psychiatry investigation · 2023Article
- Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank.Nature human behaviour · 2023Article
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundData on the association between free-living daytime sunlight exposure and incident dementia are scarce. The objective is to evaluate whether the time spent in outdoor light is related to the dementia risk and to investigate whether the optimal duration varies with clinical parameters.
methodsData were from a prospective cohort of 362,094 UK Biobank participants. A questionnaire survey was conducted to investigate how many hours the participants spent outdoors on typical summer and winter days. A restricted cubic spline (RCS) was performed to explore the potential nonlinear relationship between sunlight exposure and the risk of dementia. We used multivariate Cox proportional hazard regression models to estimate the hazard ratios (HRs) for the associations between sunlight exposure and dementia outcomes, with the change points as a reference.
resultsAfter a median follow-up of 9.0 years, 4149 (1.15%) individuals were diagnosed with dementia. RCS showed a J-shaped relationship between time spent in outdoor light and the dementia risk, with the lowest risk at three change points (1.5 h/day on average, 2 h/day in summer, and 1 h/day in winter). Cox hazard regression models showed a marked increase in risk at low exposure (HR=1.287, 95%CI 1.094-1.515) but a relatively slow increase at higher exposure (HR=1.070, 95%CI 1.031-1.10). Results are more pronounced among participants over 60 years old, females, and those with exactly 7 h of sleep every night.
conclusionsSunlight exposure had a J-shaped association with dementia risk. Giving detailed guidance on sunlight exposure can effectively prevent dementia.
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