Evidence map›Paper›PMID 35462534›Full record

ArticleBMC medical informatics and decision making2022

Predicting in-hospital length of stay: a two-stage modeling approach to account for highly skewed data.

Zhenhui Xu, Congwen Zhao, Charles D Scales, Ricardo Henao, Benjamin A Goldstein

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhenhui XuDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1104, Durham, NC, 27705, USA.
Congwen ZhaoDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1104, Durham, NC, 27705, USA.
Charles D ScalesDuke Clinical Research Institute, Duke University, Durham, NC, USA.
Ricardo HenaoDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1104, Durham, NC, 27705, USA.
Benjamin A GoldsteinDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1104, Durham, NC, 27705, USA. ben.goldstein@duke.edu.
Duke University · USClinical Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the early stages of the COVID-19 pandemic our institution was interested in forecasting how long surgical patients receiving elective procedures would spend in the hospital. Initial examination of our models indicated that, due to the skewed nature of the length of stay, accurate prediction was challenging and we instead opted for a simpler classification model. In this work we perform a deeper examination of predicting in-hospital length of stay.

methodsWe used electronic health record data on length of stay from 42,209 elective surgeries. We compare different loss-functions (mean squared error, mean absolute error, mean relative error), algorithms (LASSO, Random Forests, multilayer perceptron) and data transformations (log and truncation). We also assess the performance of two stage hybrid classification-regression approach.

resultsOur results show that while it is possible to accurately predict short length of stays, predicting longer length of stay is extremely challenging. As such, we opt for a two-stage model that first classifies patients into long versus short length of stays and then a second stage that fits a regresssor among those predicted to have a short length of stay. DISCUSSION: The results indicate both the challenges and considerations necessary to applying machine-learning methods to skewed outcomes.

conclusionsTwo-stage models allow those developing clinical decision support tools to explicitly acknowledge where they can and cannot make accurate predictions.

Indexed as

COVID-19PandemicsHospitalsHumansLength of StayMachine LearningClinical decision supportElectronic health recordsMachine learningSurgical outcomes

Identifiers

PMID35462534
PMCPMC9035272
OpenAlexW4224308809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.