Evidence map›Paper›PMID 35462518›Full record

ReviewZhonghua shao shang yu chuang mian xiu fu za zhi2022

[Research advances on thymosin β4 in promoting wound healing].

Y X Gao, L F Wang, S J Ba, J L Cao, F Li, B Li, Biao Zhou

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua shao shang yu chuang mian xiu fu za zhi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. [Research advances of natural biomaterials in promoting wound repair].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Y X GaoDepartment of Burns, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China.
L F WangDepartment of Burns, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China.
S J BaDepartment of Burns, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China.
J L CaoDepartment of Burns, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China.
F LiBurn Medical Institute of Inner Mongolia Autonomous Region, Baotou 014010, China.
B LiBurn Medical Institute of Inner Mongolia Autonomous Region, Baotou 014010, China.
Biao ZhouDepartment of Burns, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China.
Third Affiliated Hospital of Inner Mongolia Medical College · CNBaotou Medical College · CN

Funding

Regional Science Foundation Project of National Natural Science Foundation of China 81660318Science and Technology Plan of Baotou City 2019P3038
6 · The paper itself

Abstract

With the aging of population and the development of social economy, the incidence of chronic wounds is increasing day by day, while the incidence of burns and trauma remains at a high level, making wound repair an increasingly concerned area in clinical practice. Thymosin β4 is a naturally occurring small molecule protein in vivo, which is widely distributed in a variety of body fluids and cells, especially in platelets. Thymosin β4 has biological activities of promoting angiogenesis, anti-inflammation, anti-apoptosis, and anti-fibrosis, and has many important functions in wound repair. Thymosin β4 has been observed to promote the healing of various wounds, such as burns, diabetic ulcers, pressure ulcers. This paper will review the molecular structure, mechanism of wound healing promotion, pharmacokinetics, and clinical application of thymosin β4, aiming to introduce its potential in wound treatment and the shortcomings of current researches.

Indexed as

ThymosinWound HealingBurnsHumansPressure UlcerThymosin beta(4)ThymosinThymosin beta(4)

Identifiers

PMID35462518
PMCPMC11704510
OpenAlexW4224860121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.