Evidence map›Paper›PMID 35462358›Full record

ArticleDermatology (Basel, Switzerland)2022

Occupational Chronic Contact Dermatitis Successfully Treated with Dupilumab: A Case Series.

Dan Slodownik, Assi Levi, Moshe Lapidoth, Shlomo Moshe

Open access · hybridAbstract read
In one paragraph

Article in Dermatology (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Beyond Avoidance: Advanced Therapies for Contact Dermatitis.The journal of allergy and clinical immunology. In practice · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dan SlodownikDepartment of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Assi LeviSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Moshe LapidothSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shlomo MosheDepartment of Environmental and Occupational Health, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOccupational contact dermatitis may progress to a chronic course with an unfavorable prognosis. Dupilumab has been shown to be effective as a treatment for moderate-to-severe atopic dermatitis as well as other types of dermatitis.

objectivesThe aim of the study was to describe cases of chronic recalcitrant occupational contact dermatitis treated with dupilumab and with long-term follow-up.

methodsA retrospective review of 6 patients treated with dupilumab for chronic occupational contact dermatitis for periods of up to 30 months was performed.

resultsAll 6 patients had a positive and sustainable response, with dermatitis clearance and the ability to sustain work tasks.

conclusionsWe report a case series of atopic and nonatopic workers with occupational chronic contact dermatitis who failed to achieve remission under various systemic modalities but did so using dupilumab. We suggest considering dupilumab treatment for recalcitrant occupational contact dermatitis.

Indexed as

Dermatitis, Allergic ContactDermatitis, AtopicDermatitis, OccupationalAntibodies, Monoclonal, HumanizedChronic DiseaseHumansSeverity of Illness IndexTreatment OutcomeAntibodies, Monoclonal, HumanizeddupilumabAllergic contact dermatitisDupilumabOccupational contact dermatitis

Identifiers

PMID35462358
PMCPMC9677867
OpenAlexW4224248172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.