ArticleDrug and alcohol dependence2022
Alcohol- and non-alcohol-related interference: An fMRI study of treatment-seeking adults with alcohol use disorder.
Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- A randomized, double-blind, placebo-controlled study of a GHSR blocker in people with alcohol use disorder.JCI insight · 2024Trial
- Negative Urgency Mediates the Effect of Family Conflict on Cannabis Positive Expectancy: The Moderating Role of Anterior Cingulate Cortex.Addiction biology · 2026Article
- Oscillatory and behavioral indices of cognitive control dysregulation in young adult binge drinkers are influenced by sex differences.Alcohol, clinical & experimental research · 2026Article
- The Impaired Response Inhibition and Salience Attribution Model of Drug Addiction: Recent Neuroimaging Evidence and Future Directions.Annual review of psychology · 2026Review
- Alcohol cue processing alters delta-band functional connectivity and theta-band network topology in alcohol use disorder: a task-based EEG study.BMC psychiatry · 2025Article
- A Meta-Analysis of Task-Based fMRI Studies on Alcohol Use Disorder.Brain sciences · 2025Review
- Brain structural magnetic resonance imaging predictors of brief intervention response in individuals with alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Article
- Facial expression analysis and machine learning for objective assessment of alcohol craving in alcohol use disorder: a study protocol.Frontiers in psychiatry · 2025Article
- Alcohol attention bias modulates neural engagement during moral processing.Social neuroscience · 2024Article
- Functional and Structural Brain Abnormalities and Clinical Characteristics of Male Patients with Alcohol Dependence.Brain sciences · 2023Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundIndividuals with alcohol use disorder (AUD) have difficulty diverting attention away from alcohol-related stimuli and towards non-alcohol-related goals (i.e., alcohol-related attention interference). It remains unclear whether regulatory brain function differs during alcohol and non-alcohol-related interference. This study compares brain reactivity during the alcohol and classic Stroop and whether such brain function relates to AUD severity.
methods46 participants with AUD completed alcohol and classic color-word Stroop tasks during fMRI. Brain activity was compared during alcohol and classic Stroop interference in the rostral and dorsal anterior cingulate cortices (rACC and dACC) and correlated with self-reported AUD severity. Exploratory whole-brain analyses were also conducted.
resultsBehavioral interference (i.e., slower reaction times) was observed during alcohol and classic Stroop. rACC activity was significantly higher during the alcohol > neutral contrast versus the incongruent > congruent contrast. dACC activity did not differ between the Stroop tasks. dACC activity during incongruent > congruent was positively associated with AUD severity.
conclusionsActivity in ACC subregions differed during alcohol and non-alcohol interference. Increased alcohol-related activity in the rACC, a region linked to emotional conflict resolution, suggests an interfering effect of self-relevant alcohol cues on non-alcohol-related processing. AUD severity was related to greater dACC reactivity during classic Stroop interference, suggesting that non-drug-related cognitive control impairments are more pronounced in those with more problematic alcohol use.
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