ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022
Reduction in the infection fatality rate of Omicron variant compared with previous variants in South Africa.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inferring the true number of SARS-CoV-2 infections in Japan.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022Pooled it
- CfDNA as a surrogate marker for COVID-19 severity in patients with influenza-like symptoms with and without SARS-CoV-2 infection in general practice: a prospective cohort study.Virology journal · 2025Article
- Exploring affordable and effective pandemic containment measures in lower-income countries with a spatial SEIR model: a case study in South Africa.BMC public health · 2025Article
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- The Impact of Vaccination Frequency on COVID-19 Public Health Outcomes: A Model-Based Analysis.Vaccines · 2025Article
- Experiences and reflections of doctors on the operations of designated clinics during the COVID-19 pandemic in Hong Kong: a qualitative study.BMC health services research · 2025Article
- Development Of the VAMPCT Score for Predicting Mortality in CKD Patients with COVID-19.International journal of medical sciences · 2025Article
- Evaluating the Usefulness of Population-Wide COVID-19 Testing in the Omicron Era: Insights from a German Model.Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2024Article
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- A novel deterioration prediction system for mild COVID-19 patients in Korea: a retrospective study.Scientific reports · 2024Article
- Public acceptance of COVID-19 control measures and associated factors during Omicron-dominant period in China: a cross-sectional survey.BMC public health · 2024Article
- Article
- From Alpha to Omicron: How Different Variants of Concern of the SARS-Coronavirus-2 Impacted the World.Biology · 2023Review
- Pre-Operative SARS-CoV-2 Testing in Asymptomatic Heart Transplantation Recipients.Biomedicines · 2023Article
- Estimating long-term vaccine effectiveness against SARS-CoV-2 variants: a model-based approach.Nature communications · 2023Article
- One Pandemic, Two Solutions: Comparing the U.S.-China Response and Health Priorities to COVID-19 from the Perspective of "Two Types of Control".Healthcare (Basel, Switzerland) · 2023Article
- Factors associated with negative conversion of viral RNA in hospitalized children infected with SARS-CoV-2 Omicron variant in Shanghai, China: a retrospective analysis.BMC infectious diseases · 2023Article
- Temporal dynamics and fatality of SARS-CoV-2 variants in Bangladesh.Health science reports · 2023Article
- Bilateral Lung Transplantation With Donor Positive for COVID-19 Infection on Bronchoalveolar Lavage: A Case Report.Transplantation proceedings · 2023Article
- Effectiveness and durability of BNT162b2 vaccine against hospital and emergency department admissions due to SARS-CoV-2 omicron sub-lineages BA.1 and BA.2 in a large health system in the USA: a test-negative, case-control study.The Lancet. Respiratory medicine · 2023Article
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4 authors.
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Abstract
objectiveThe SARS-CoV-2 Omicron (B.1.1.529) variant has caused global concern. Previous studies have shown that the variant has enhanced immune evasion ability and transmissibility and reduced severity.
methodsIn this study, we developed a mathematical model with time-varying transmission rate, vaccination, and immune evasion. We fit the model to reported case and death data up to February 6, 2022 to estimate the transmissibility and infection fatality ratio of the Omicron variant in South Africa.
resultsWe found that the high relative transmissibility of the Omicron variant was mainly due to its immune evasion ability, whereas its infection fatality rate substantially decreased by approximately 78.7% (95% confidence interval: 66.9%, 85.0%) with respect to previous variants.
conclusionOn the basis of data from South Africa and mathematical modeling, we found that the Omicron variant is highly transmissible but with significantly lower infection fatality rates than those of previous variants of SARS-CoV-2.
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