Evidence map›Paper›PMID 35461889›Full record

ArticleGastrointestinal endoscopy2022

Pre-endoscopy coronavirus disease 2019 screening and severe acute respiratory syndrome coronavirus-2 nucleic acid amplification testing in the Veterans Affairs healthcare system: clinical practice patterns, outcomes, and relationship to procedure volume.

Andrew J Gawron, Shahnaz Sultan, Thomas J Glorioso, Sophia Califano, Stephen M Kralovic, Makoto Jones, Susan Kirsh, Jason A Dominitz

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastrointestinal endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04389957 (Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04389957 completednot on this map

Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System

TypeobservationalSponsorVA Office of Research and DevelopmentRan2020 to 2024Enrolled445ConditionsColorectal NeoplasmsArmsVeterans Affairs Endoscopy Quality Improvement Program (VA-EQuIP)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Andrew J GawronNational Gastroenterology and Hepatology Program, Office of Specialty Care Services, Department of Veterans Affairs, Washington, DC, USA; VA Salt Lake City Health Care System, Salt Lake City, Utah, USA; Division of Gastroenterology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Shahnaz SultanDivision of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis VAHCS, Minneapolis, Minnesota, USA.
Thomas J GloriosoCART Program, Office of Quality and Patient Safety, Veterans Health Administration, Washington, DC, USA.
Sophia CalifanoPreventive Medicine, National Center for Health Promotion and Disease Prevention, Veterans Health Administration, Washington, DC, USA; General Internal Medicine, Duke University, Durham, North Carolina, USA.
Stephen M KralovicNational Infectious Diseases Service, Office of Specialty Care Services, Department of Veterans Affairs, Washington, DC, USA; Medical Service, Cincinnati VA Medical Center, Cincinnati, Ohio, USA; Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Makoto JonesVA Salt Lake City Health Care System, Salt Lake City, Utah, USA; Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Susan KirshOffice of Veterans Access to Care, Veterans Health Administration, Washington, DC, USA.
Jason A DominitzNational Gastroenterology and Hepatology Program, Office of Specialty Care Services, Department of Veterans Affairs, Washington, DC, USA; VA Puget Sound Health Care System, Seattle, Washington, USA; Division of Gastroenterology, University of Washington School of Medicine, Seattle, Washington, USA.
University of Utah · USVeterans Health Administration · USCincinnati VA Medical Center · USDuke University · USUniversity of Minnesota · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe coronavirus disease 2019 (COVID-19) pandemic has had profound impacts worldwide, including on the performance of GI endoscopy. We aimed to describe the performance and outcomes of pre-endoscopy COVID-19 symptom and exposure screening and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) nucleic acid amplification testing (NAAT) across the national Veterans Affairs healthcare system and describe the relationship of SARS-CoV-2 NAAT use and resumption of endoscopy services.

methodsCOVID-19 screening and NAAT results from March 2020 to April 2021 were analyzed to determine use, performance characteristics of screening, and association between testing and endoscopic volume trends.

resultsOf 220,891 completed endoscopies identified, 115,890 (52.5%) had documented preprocedure COVID-19 symptom and exposure screenings and 154,127 (69.8%) had preprocedure NAAT results within 7 days before scheduled endoscopy. Of 131,894 total canceled endoscopies, 26,475 (20.1%) had screening data and 28,505 (21.6%) had SARS-CoV-2 NAAT results. Overall, positive NAAT results were reported in 1.8% of all individuals tested and in 1.3% of those who screened negative. Among completed and canceled endoscopies, COVID-19 screening had a 34.6% sensitivity (95% confidence interval [CI], 32.4%-36.8%) and 96.4% specificity (95% CI, 96.2%-96.5%) when compared with NAAT. COVID-19 screening had a positive predictive value of 15.0% (95% CI, 14.0%-16.1%) and a negative predictive value of 98.7% (95% CI, 98.7%-98.8%). There was a very weak correlation between monthly testing and monthly endoscopy volume by site (Spearman rank correlation coefficient = .09).

conclusionsThese findings have important implications for decisions about preprocedure testing, especially given breakthrough infections among vaccinated individuals during the SARS-CoV-2 delta and omicron variant surge.

Indexed as

COVID-19Nucleic AcidsVeteransEndoscopy, GastrointestinalHumansPractice Patterns, Physicians'SARS-CoV-2Nucleic Acids

Identifiers

PMID35461889
PMCPMC9023088
OpenAlexW4224288627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.